Evidence map›Paper›PMID 30271793›Full record

ArticleJournal of immunology research2018

Differences of Clonogenic Mesenchymal Stem Cells on Immunomodulation of Lymphocyte Subsets.

Pascual Martínez-Peinado, Sandra Pascual-García, Enrique Roche, José Miguel Sempere-Ortells

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Pascual Martínez-PeinadoImmunology Division, Biotechnology Department, University of Alicante, San Vicente del Raspeig, Alicante, Spain.ORCID 0000-0003-4370-5468
Sandra Pascual-GarcíaImmunology Division, Biotechnology Department, University of Alicante, San Vicente del Raspeig, Alicante, Spain.ORCID 0000-0002-0536-1185
Enrique RocheBiochemistry and Cell Therapy Unit, Institute of Bioengineering, University Miguel Hernandez, Elche, Alicante, Spain.
José Miguel Sempere-OrtellsImmunology Division, Biotechnology Department, University of Alicante, San Vicente del Raspeig, Alicante, Spain.
University of Alicante · ESUniversitat de Miguel Hernández d'Elx · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSC) are a widely used population in cell therapy for their ability to differentiate into distinct tissues and more lately, for their immunomodulatory properties. However, the use of heterogeneous populations could be responsible for the nondesired outcomes reflected in the literature. Here, we analyse the different capacities of five one-cell-derived MSC clones to exert their immunomodulation ex vivo. We assessed proliferation assays in cocultures of MSC clones and purified cluster of differentiation (CD)3

Indexed as

Antigens, CDCell DifferentiationCell ProliferationCells, CulturedClone CellsCoculture TechniquesHumansImmunomodulationLymphocyte ActivationLymphocyte CountMesenchymal Stem CellsTh1 CellsTh2 CellsT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsAntigens, CD

Identifiers

PMID30271793
PMCPMC6151204
OpenAlexW2892355804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.