ArticleACS sustainable chemistry & engineering2018
Understanding Lignin Aggregation Processes. A Case Study: Budesonide Entrapment and Stimuli Controlled Release from Lignin Nanoparticles.
Article in ACS sustainable chemistry & engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 236 citations in OpenAlex.
- Impact of Type of Lignin, Alkaline and Lignosulfonate, on Release and Soil Adsorption of Methoxyfenozide Delivered with Lignin-ACS omega · 2026Article
- Recovery of Monoethanolammonium Acetate from Ionosolv Liquors Using a γ-Valerolactone-Based Aqueous Two-Phase System.ChemSusChem · 2026Article
- Photo and Thermal Stable Lignin-Based Sunscreen Microcapsules.Chem & bio engineering · 2026Article
- Impact of Lignin Type on Yield and Fiber Morphology in Biobased Carbon Fiber Precursors.ACS omega · 2026Article
- Threshold-Filtered Kinetic Monte Carlo Simulation for Real-Time Simulation and Control of Biomass Fractionation.Industrial & engineering chemistry research · 2026Article
- Synthesis of lignin nanoparticles using CORSC advances · 2026Article
- Entanglement-Mediated Dispersion of Lignin Nanoparticles in PVA Networks for Transparent and Tough Bio-Composites.Polymers · 2026Article
- Colloidal lignin particles for Pickering emulsion stabilization: multifunctional properties and prospects for cosmetic applications.Natural products and bioprospecting · 2026Review
- Alcohol-Decorated Lignins for Nanoparticle Formation through Reactive Fractionation in Ternary Deep Eutectic Solvent Systems.ACS sustainable chemistry & engineering · 2026Article
- Engineering of Industrial Kraft Lignin: The Role of Esterification Methods in Lignin Nanoparticle Self-Assembly.Biomacromolecules · 2025Article
- Lignin Dissolution and Direct Ultrasmall-Lignin-Nanoparticle Formation in Acidic and Alkaline Deep Eutectic Solvents: A Molecular-Level Insight.Angewandte Chemie (International ed. in English) · 2025Article
- Spontaneous and Laccase-Assisted Adsorption of Hemicelluloses Rendering Colloidal Stability of Lignin Nanoparticles at Low pH.ChemSusChem · 2025Article
- Interfacial Properties of Surface-Modified Lignin Nanoparticles.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Lignin-Derived Sustainable Nano-Platforms: A Multifunctional Solution for an Efficient Dye Removal.ChemSusChem · 2024Article
- Article
- Modeling the Production Process of Lignin Nanoparticles Through Anti-Solvent Precipitation for Properties Prediction.Nanomaterials (Basel, Switzerland) · 2024Article
- Characterization and structural analysis of alcohol-fractionated lignin biofuels processed at ambient temperature.Heliyon · 2024Article
- Overcoming Challenges of Lignin Nanoparticles: Expanding Opportunities for Scalable and Multifunctional Nanomaterials.Accounts of chemical research · 2024Article
- Spray Coating of Wood with Nanoparticles from Lignin and Polylactic Glycolic Acid Loaded with Thyme Essential Oils.Polymers · 2024Article
- Molecular insights into the bonding mechanisms between selenium and dissolved organic matter.The Science of the total environment · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mechanism of lignin nanoprecipitation and subsequent self-assembly was elucidated by studying generation of lignin nanoparticles (LNPs) from aqueous ethanol. LNP formation was found to follow a kinetically controlled nucleation-growth mechanism in which large lignin molecules formed the initial critical nuclei. Using this information, we demonstrate entrapment of budesonide in LNPs and subsequent pH-triggered and surfactant-responsive release of this synthetic anti-inflammatory corticosteroid. Overall, our results not only provide a promising intestinal delivery system for budesonide but also deliver fundamental mechanistic understanding for the entrapment of actives in LNPs with controlled size and release properties.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.