Evidence map›Paper›PMID 30271671›Full record

ArticleInternational journal of privacy and health information management

Diabetes-Related Cognitive Decline, a Global Health Issue, and New Treatments Approaches.

Vera Novak, Federico Gomez, Alexandre Campos Dias, Daniela A Pimentel, Freddy J Alfaro

Abstract read
In one paragraph

Article in International journal of privacy and health information management. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Online Gaming During the COVID-19 Pandemic in India: Strategies for Work-Life Balance.International journal of mental health and addiction · 2022
    Article
  4. Article
  5. Presence of White Matter Lesions Associated with Diabetes-Associated Cognitive Decline in Male Rat Models of Pre-Type 2 Diabetes.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vera NovakBeth Israel Deaconess Medical Center, Boston, MA, USA.
Federico GomezBeth Israel Deaconess Medical Center, Boston, MA, USA.
Alexandre Campos DiasBeth Israel Deaconess Medical Center, Boston, MA, USA.
Daniela A PimentelUniversity of Massachusetts Medical School, Worchester, MA, USA.
Freddy J AlfaroBeth Israel Deaconess Medical Center, Boston, MA, USA.

Funding

Memory Advancement by Intranasal Insulin in Type 2 Diabetes (MemAID)R01DK103902 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI NOVAK, VERA · 2015 to 2019
$3.7M
Cerebromicrovascular disease in elderly with diabetesR01AG028076 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI NOVAK, VERA · 2009 to 2010
$1.2M
Enhancing cerebral vasoreativity & cognition by intranasal insulin in T2DMR21DK084463 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI NOVAK, VERA · 2010 to 2011
$466k
NIA NIH HHS R01 AG028076NIDDK NIH HHS R01 DK103902NIDDK NIH HHS R21 DK084463
6 · The paper itself

Abstract

The epidemic of type 2 diabetes (T2DM) is spreading around the globe and challenging the unprecedented success of health sciences in increasing longevity. T2DM has been linked to accelerated brain aging, functional decline in older adults and dementia. Brain insulin resistance and glycemic variability are potential mechanisms underlying T2DM-related brain damage and cognitive decline. Intranasal insulin therapy has emerged as a potential new treatment for T2DM-related cognitive impairment. Wearable technologies now allow better monitoring of behaviors and glycemic levels over several days and deliver real time feedback that can be used to improve self-management and lead to new prevention strategies and therapies for T2DM complications.

Indexed as

Glycemic VariabilityIntranasal InsulinType 2 DiabetesWearable Technology

Identifiers

PMID30271671
PMCPMC6159895

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.