ArticleJournal of pharmaceutics2018
Antimicrobial Resistance Profile of Different Clinical Isolates against Third-Generation Cephalosporins.
Article in Journal of pharmaceutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- High rate of extended-spectrum beta-lactamase-producing gram-negative infections and associated mortality in Ethiopia: a systematic review and meta-analysis.Antimicrobial resistance and infection control · 2020Pooled it
- Prioritization of antimicrobial resistance surveillance of gram-negative pathogens - a stacked modelling approach.Wellcome open research · 2026Article
- Ceftriaxone Resistance in the Surgical Adult Intensive Care Unit at Muhimbili National Hospital, Dar es Salaam, Tanzania.The East African health research journal · 2025Article
- Article
- Assessment of bacterial profile, antimicrobial susceptibility status, and associated factors of isolates among hospitalized patients at Dessie Comprehensive Specialized Hospital, Northeast Ethiopia.BMC microbiology · 2024Article
- Isolation, and Identification ofInfection and drug resistance · 2024Article
- Prevalence and antibiotic resistance profile of UTI-causing uropathogenic bacteria in diabetics and non-diabetics at the Maternity and Children Hospital in Jeddah, Saudi Arabia.Frontiers in microbiology · 2024Article
- The respiratory chain ofFrontiers in microbiology · 2024Article
- Photoinduced behaviour of N,N-bidentate manganese(I) and rhenium(I) tricarbonyl complexes for singlet oxygen generation and CO release.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024Article
- Antimicrobial resistance profiles of bacterial isolates from clinical specimens referred to Ethiopian Public Health Institute: analysis of 5-year data.BMC infectious diseases · 2023Article
- Evaluating the Potency of Selected Antibiotic Medications Dispensed in Community Pharmacies in Gwale, Kano, Nigeria.Antibiotics (Basel, Switzerland) · 2023Article
- Probiotic potential ofHeliyon · 2023Article
- Molecular detection of plasmid mediated blaAnnals of clinical microbiology and antimicrobials · 2023Article
- Article
- Prevalence and antimicrobial susceptibility profile of bacteria isolated from the hands of housemaids in Jimma City, Ethiopia.Frontiers in public health · 2023Article
- Article
- Ceftriaxone resistance among patients at GAMBY teaching general hospital.Scientific reports · 2022Article
- Antibiotic resistance and siderophores production by clinicalBiotechnologia · 2022Article
- Emergence of High Prevalence of Extended-Spectrum Beta-Lactamase and Carbapenemase-ProducingBioMed research international · 2022Article
- Different Nanotechnology Approaches for Ciprofloxacin Delivery Against Multidrug-Resistant Microbes.Infection and drug resistance · 2022Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDrug resistant microorganisms lead to an increase in morbidity and mortality as they boost the risk of inappropriate therapy. Hence, data on antimicrobial resistance help define the best possible treatment for individual patients. Therefore, this study aimed to screen the antimicrobial resistant profile of 3rd generation cephalosporin drugs in Jimma University Specialized Teaching Hospital.
methodsA hospital based prospective cross-sectional study was conducted in Jimma University Specialized Hospital (JUSH) from April to August 2016. The clinical samples such as wound swab, urine, sputum, and stool were collected from hospitalized patients. Then, bacterial species were isolated and identified as per the standard microbiological methods. Antimicrobial susceptibility tests were carried out using various antimicrobial discs by Kirby-Bauer disc diffusion method.
resultsTotally, 248 bacterial isolates were obtained from 154 (62.1%) male and 94 (37.9%) female patients.
conclusionBacterial resistance towards third-generation cephalosporin (ceftriaxone and ceftazidime) is escalating as more than half of the isolated strains demonstrated resistance to these drugs. Moreover, these strains also revealed multidrug resistance mainly against clinically used drugs which could render therapy unsuccessful. Therefore, in clinical use appropriate medications should be selected based on the data obtained from antimicrobial susceptibility tests.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.