Evidence map›Paper›PMID 30271598›Full record

ArticleBiomedical reports2018

Influence of initiation time and white blood cell count on the efficacy of cytotoxic agents in acute promyelocytic leukemia during induction treatment.

Fang Xu, Chang-Xin Yin, Chun-Li Wang, Bing-Jie Ding, Qing-Xiu Zhong, Xue-Jie Jiang, Ling Jiang, Zhi-Xiang Wang, Fan-Yi Meng

Open access · diamondAbstract read
In one paragraph

Article in Biomedical reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Fang XuHematology Department, Mianyang Central Hospital, Mianyang, Sichuan 621000, P.R. China.
Chang-Xin YinHematology Department, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Chun-Li WangHematology Department, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Bing-Jie DingHematology Department, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Qing-Xiu ZhongHematology Department, Kanghua Hospital, Dongguan, Guangdong 523080, P.R. China.
Xue-Jie JiangHematology Department, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Ling JiangHematology Department, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Zhi-Xiang WangHematology Department, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Fan-Yi MengHematology Department, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Nanfang Hospital · CNGuhua Hospital · CNMianyang Central Hospital · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study retrospectively analyzed 96 newly diagnosed acute promyelocytic leukemia (APL) patients with low-intermediate mortality risk to identify the optimum timing to initiate cytotoxic chemotherapy following all-trans retinoic acid (ATRA) administration. Based on white blood cell (WBC) at chemotherapy initiation, the patients were divided into three groups: low WBC (WBC count ≤4×10

Indexed as

acute promyelocytic leukemiachemotherapyinduction treatmentinitiation timelow-intermediate riskprognosis

Identifiers

PMID30271598
PMCPMC6158397
OpenAlexW2810757164

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.