Evidence map›Paper›PMID 30271590›Full record

SynthesisF1000Research2018

Virologic failure and HIV drug resistance on simplified, dolutegravir-based maintenance therapy: Systematic review and meta-analysis.

Gilles Wandeler, Marta Buzzi, Nanina Anderegg, Delphine Sculier, Charles Béguelin, Matthias Egger, Alexandra Calmy

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. A systematic review of the genetic mechanisms of dolutegravir resistance.The Journal of antimicrobial chemotherapy · 2019
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Tenofovir alafenamide plus dolutegravir as a switch strategy in HIV-infected patients: a pilot randomized controlled trial.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2023
    Trial
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  9. Trial
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Structural Biology of HIV Integrase Strand Transfer Inhibitors.Trends in pharmacological sciences · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gilles Wandeler *Department of Infectious Diseases, Bern University Hospital, Bern, 3010, Switzerland.ORCID 0000-0002-5278-8763
Marta Buzzi *Division of Infectious Diseases, Geneva University Hospital, Geneva, 1205, Switzerland.
Nanina AndereggInstitute of Social and Preventive Medicine, University of Bern, Bern, 3012, Switzerland.
Delphine SculierDivision of Infectious Diseases, Geneva University Hospital, Geneva, 1205, Switzerland.
Charles BéguelinDepartment of Infectious Diseases, Bern University Hospital, Bern, 3010, Switzerland.
Matthias EggerInstitute of Social and Preventive Medicine, University of Bern, Bern, 3012, Switzerland.
Alexandra CalmyDivision of Infectious Diseases, Geneva University Hospital, Geneva, 1205, Switzerland.ORCID 0000-0002-1137-6826

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HIV InfectionsAdultAnti-HIV AgentsDolutegravirDrug Resistance, ViralFemaleHeterocyclic Compounds, 3-RingHumansMaleMiddle AgedObservational Studies as TopicOxazinesPiperazinesPyridonesAnti-HIV AgentsDolutegravirHeterocyclic Compounds, 3-RingOxazinesPiperazinesPyridonesDolutegravirHIVmeta-analysissimplified therapy

Identifiers

PMID30271590
PMCPMC6134332

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.