ReviewF1000Research2018
Recent advances in understanding and managing infantile colic.
Review in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06727760 (Investigation of the Effects of Colic Massage and Kangaroo Care on Colicky Infants and Their Mothers), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation of the Effects of Colic Massage and Kangaroo Care on Colicky Infants and Their Mothers
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Safety and efficacy of adding postbiotics in infant formula: a systematic review and meta-analysis.Pediatric research · 2024Pooled it
- Osteopathic treatment of infants with infantile colic/excessive crying: a prospective, multicentric, randomized controlled trial and nested observational trial.BMC pediatrics · 2025Trial
- A synbiotic mixture for the management of infantile colic: A randomized trial.European journal of pediatrics · 2024Trial
- Attitude, Self-Reported Practices and Knowledge of Pediatricians Regarding the Recommendation of Goat-Milk-Based Formula for Management of Infantile Colic: A Cross-Sectional Study in Saudi Arabia.Healthcare (Basel, Switzerland) · 2026Article
- Why do babies cry? Exploring the role of the gut microbiota in infantile colic, constipation, and cramps in the KOALA birth cohort study.Gut microbes · 2025Article
- Comparative Analysis of Breastfeeding and Infant Formulas: Short- and Long-Term Impacts on Infant Nutrition and Health.Food science & nutrition · 2025Review
- Breaking the cycle: Psychological and social dimensions of pediatric functional gastrointestinal disorders.World journal of clinical pediatrics · 2025Article
- Article
- Maternal knowledge and practices regarding infantile colic in Palestine: a need for enhanced education and awareness.BMC pregnancy and childbirth · 2025Article
- Article
- Probiotics for Neurodegenerative Diseases: A Systemic Review.Microorganisms · 2023Review
- Infantile Colic and Long-Term Outcomes in Childhood: A Narrative Synthesis of the Evidence.Nutrients · 2023Review
- Exploring cultural determinants to be integrated into preterm infant care in the neonatal intensive care unit: an integrative literature review.BMC pregnancy and childbirth · 2023Review
- Postbiotics in Human Health: A Narrative Review.Nutrients · 2023Review
- Effectiveness of a starch thickened infant formula with reduced lactose content, probiotics and prebiotics on quality of life and clinical outcome in infants with regurgitation and/or colic.Frontiers in nutrition · 2023Article
- Review
- Incidence and Associated Factors of Infantile Colic in Thai Infants.Pediatric gastroenterology, hepatology & nutrition · 2022Article
- Clinical efficacy of magnetotherapy combined with pediatric massage on infantile colic.American journal of translational research · 2022Article
- Extracellular membrane vesicles fromFrontiers in microbiology · 2022Article
- How Do Mothers Take Care of Their Infants with Colic Pain? A Mixed-Method Study.Ethiopian journal of health sciences · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A newborn brings joy to the family. Crying belongs to the spectrum of normal behaviour of young infants. However, although it occurs in about 20% of all infants, unsoothable and persistent crying in young infants distresses the family, although it is usually benign. The aetiology of infantile colic remains unknown, although an unbalanced gastro-intestinal microbiome, increased intestinal permeability, and chronic inflammation are involved, as well as behavioural factors, including over- and under-stimulation. It is a challenge for healthcare professionals to decide when organic disease needs to be excluded. Parental stress is a reason for babies to cry more, inducing a vicious cycle. Therefore, parental reassurance with explanatory guidance is the cornerstone of management. The placebo effect is estimated to be as high as 50%. If an intervention is felt to be necessary to offer further support to the baby and family, it is important to choose the options for which there is some efficacy without adverse effects. There is evidence that some specific probiotic strains such as
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.