Evidence map›Paper›PMID 30271504›Full record

ReviewJournal of Cancer2018

The Significance of Liquid Biopsy in Pancreatic Cancer.

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Potential role of microRNAs in pancreatic cancer manifestation: a review.Journal of the Egyptian National Cancer Institute · 2022
    Review
  12. Review
  13. Review
  14. Review
  15. Liquid Biopsy for Cancer Cachexia: Focus on Muscle-Derived microRNAs.International journal of molecular sciences · 2021
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Zi-Hao QiDepartment of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Hua-Xiang XuDepartment of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Shi-Rong ZhangDepartment of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Jin-Zhi XuDepartment of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Shuo LiDepartment of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
He-Li GaoDepartment of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Wei JinDepartment of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Wen-Quan WangDepartment of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Chun-Tao WuDepartment of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Quan-Xing NiDepartment of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Xian-Jun YuDepartment of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Liang LiuDepartment of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Shanghai Medical College of Fudan University · CNFudan University Shanghai Cancer Center · CNShanghai Cancer Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of cancer. The 5-year survival rate for PDAC remains low because it is always diagnosed at an advanced stage and it is resistant to therapy. A biomarker, which could detect asymptomatic premalignant or early malignant tumors and predict the response to treatment, will benefit patients with PDAC. However, traditional biopsy has its limitations. There is an urgent need for a tumor biomarker that could easily and repeatedly sample and monitor, in real time, the progress of tumor development. Liquid biopsy could be a tool to assess potential biomarkers. In this review, we focused on the latest discoveries and advancements of liquid biopsy technology in pancreatic cancer research and demonstrated how this technology is being used in clinical applications.

Indexed as

Cell-free nucleic acidCirculating tumor cellsExosomesLiquid biopsyPancreatic cancer

Identifiers

PMID30271504
PMCPMC6160675
OpenAlexW2890542394

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.