Evidence map›Paper›PMID 30271413›Full record

ArticleFrontiers in plant science2018

New Urea Derivatives Are Effective Anti-senescence Compounds Acting Most Likely via a Cytokinin-Independent Mechanism.

Jaroslav Nisler, Marek Zatloukal, Roman Sobotka, Jan Pilný, Barbora Zdvihalová, Ondrej Novák, Miroslav Strnad, Lukáš Spíchal

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Targeting Cytokinin Homeostasis in Rapid CyclingPlants (Basel, Switzerland) · 2020
    Article
  7. Article
  8. Article
  9. Role of Cytokinins in Senescence, Antioxidant Defence and Photosynthesis.International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jaroslav NislerLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany AS CR & Palacký University, Olomouc, Czechia.
Marek ZatloukalDepartment of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Palacký University, Olomouc, Czechia.
Roman SobotkaLaboratory of Photosynthesis, Centre Algatech, Institute of Microbiology, Třeboň, Czechia.
Jan PilnýLaboratory of Photosynthesis, Centre Algatech, Institute of Microbiology, Třeboň, Czechia.
Barbora ZdvihalováLaboratory of Photosynthesis, Centre Algatech, Institute of Microbiology, Třeboň, Czechia.
Ondrej NovákLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany AS CR & Palacký University, Olomouc, Czechia.
Miroslav StrnadLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany AS CR & Palacký University, Olomouc, Czechia.
Lukáš SpíchalDepartment of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Palacký University, Olomouc, Czechia.
Palacký University Olomouc · CZCzech Academy of Sciences, Institute of Microbiology · CZCzech Academy of Sciences, Institute of Experimental Botany · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stress-induced senescence is a global agro-economic problem. Cytokinins are considered to be key plant anti-senescence hormones, but despite this practical function their use in agriculture is limited because cytokinins also inhibit root growth and development. We explored new cytokinin analogs by synthesizing a series of 1,2,3-thiadiazol-5-yl urea derivatives. The most potent compound, 1-(2-methoxy-ethyl)-3-1,2,3-thiadiazol-5-yl urea (ASES - Anti-Senescence Substance), strongly inhibited dark-induced senescence in leaves of wheat (

Indexed as

ASEScytokininphotosystem IIsenescencestressthidiazuronwheat

Identifiers

PMID30271413
PMCPMC6142817
OpenAlexW2891808011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.