Evidence map›Paper›PMID 30271394›Full record

ReviewFrontiers in microbiology2018

Promising Antibiofilm Activity of Peptidomimetics.

Rafael Gomes Von Borowski, Simone Cristina Baggio Gnoatto, Alexandre José Macedo, Reynald Gillet

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The activity of antimicrobial peptoids against multidrug-resistant ocular pathogens.Contact lens & anterior eye : the journal of the British Contact Lens Association · 2024
    Article
  6. Article
  7. Peptidomimetics in cancer targeting.Molecular medicine (Cambridge, Mass.) · 2022
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Solid-Phase Insertion ofMolecules (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rafael Gomes Von BorowskiUniv Rennes, CNRS, Institut de Génétique et Développement de Rennes (IGDR), UMR 6290, Rennes, France.
Simone Cristina Baggio GnoattoPrograma de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Biotechnology Center, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Alexandre José MacedoPrograma de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Biotechnology Center, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Reynald GilletUniv Rennes, CNRS, Institut de Génétique et Développement de Rennes (IGDR), UMR 6290, Rennes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogenic biofilms are a global health care concern, as they can cause extensive antibiotic resistance, morbidity, mortality, and thereby substantial economic loss. Scientific efforts have been made over the past few decades, but so far there is no effective treatment targeting the bacteria in biofilms. Antimicrobial peptidomimetics have been proposed as promising potential anti-biofilm agents. Indeed, these structurally enhanced molecules can mimic the action of peptides but are not susceptible to proteolysis or immunogenicity, the characteristic limitations of natural peptides. Here, we provide insights into antibiofilm peptidomimetic strategies and molecular targets, and discuss the design of two major peptidomimetics classes: AApeptides (

Indexed as

AApeptidesantibiotic resistancebiofilmpeptidespeptidomimeticspeptoids

Identifiers

PMID30271394
PMCPMC6146102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.