ArticleSeparation and purification technology2018
Evaluation of the effect of ionic liquids as adjuvants in polymer-based aqueous biphasic systems using biomolecules as molecular probes.
Article in Separation and purification technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Volumetric, acoustic, and computational investigation of l-threonine and glycyl-l-threonine interactions in aqueous 1-octyl-3-methylimidazolium bromide solutions.RSC advances · 2026Article
- Separation of phenyl acetic acid and 6-aminopenicillanic acid applying aqueous two-phase systems based on copolymers and salts.Scientific reports · 2021Article
- Extraction and Purification of Capsaicin from Capsicum Oleoresin Using a Combination of Tunable Aqueous Polymer-Phase Impregnated Resin (TAPPIR) Extraction and Chromatography Technology.Molecules (Basel, Switzerland) · 2019Article
- Understanding the Effect of Ionic Liquids as Adjuvants in the Partition of Biomolecules in Aqueous Two-Phase Systems Formed by Polymers and Weak Salting-Out Agents.Biochemical engineering journal · 2019Article
- Potential of Aqueous Two-Phase Systems for the Separation of Levodopa from Similar Biomolecules.Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986) · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Aqueous biphasic systems (ABS) have been largely investigated for the extraction, separation and/or purification of biomolecules. Recently, the use of ionic liquids (ILs) as additives in conventional polymer-based ABS was proposed to overcome the limited range of polarities of the coexisting phases. However, the impact of ILs on the partitioning of biomolecules on IL additivated ABS is not universal and is still poorly understood. Aiming at obtaining additional insights on this matter, the effects of the chemical structure of the IL, tie-line length (TLL) and biomolecule nature upon the partition of a series of model biomolecules were investigated. For this purpose, ternary ABS (composed of polyethylene glycol (PEG) 400, citrate buffer at pH 7.0, and water), and several quaternary ABS (composed of PEG 400, citrate buffer at pH 7.0, water and ILs at 5 wt%), were prepared using different chloride-based ILs ([C
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Registered trials
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