ReviewSarcoma2018
Benign Smooth Muscle Tumors (Leiomyomas) of Deep Somatic Soft Tissue.
Review in Sarcoma, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Smooth Muscle Tumor of Uncertain Malignant Potential (STUMP): A Systematic Review of the Literature in the Last 20 Years.Current oncology (Toronto, Ont.) · 2024Pooled it
- Skull Base Leiomyomas and Angioleiomyomas: A Systematic Literature Review and an Uncommon Case Report.World neurosurgery · 2021Pooled it
- Case Report: Parapharyngeal Leiomyosarcoma Mimicking Neurofibroma.Clinical case reports · 2026Article
- Article
- Benign Cutaneous Neoplasms with Syndromic Associations.Dermatopathology (Basel, Switzerland) · 2025Review
- PCMR: a comprehensive precancerous molecular resource.Scientific data · 2025Article
- Primary omental smooth muscle tumor in an adult male: a diagnostic dilemma for leiomyoma: a case report.Journal of medical case reports · 2024Article
- Incidental deep soft tissue leiomyoma of the groin - a case report and comprehensive review of literature.Journal of surgical case reports · 2024Article
- Vulvar Leiomyoma Masquerading as Bartholin Cyst: A Case Report of Unveiled Diagnosis and Surgical Management.Cureus · 2023Article
- Minimally Invasive Image-Guided Transgluteal Approach for Resection of a Sciatic Nerve Tumor: A Technical Note.Cureus · 2023Article
- Calcified deep somatic soft tissue leiomyoma of the leg: A case report.SAGE open medical case reports · 2023Article
- Large renal leiomyoma: A multidisciplinary approach to diagnosis.Journal of radiology case reports · 2021Article
- Calcified Leiomyoma of the Distal Forearm in a Child: A Case Report and Review of Literature.Case reports in orthopedics · 2020Article
- Low-grade Fibromyxoid Sarcoma With Massive Degeneration: A Case of Unusual Gross and Histological Features.In vivo (Athens, Greece)Article
- Endobronchial angioleiomyoma: Diagnostic difficulties of a rare lung neoplasm.Annals of thoracic medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leiomyomas of deep soft tissue are extremely rare and should only be diagnosed following adherence to stringent histological criteria, namely, the absence of nuclear atypia and of coagulative tumor necrosis. Whether extremely low counts of, or even any, mitotic activity are acceptable when making a diagnosis of leiomyoma in deep soft tissue sites is controversial. The morphology and immunophenotype of smooth muscle tumors in deep soft tissue are similar to their counterparts irrespective of topography. It is interesting to note that leiomyomas of deep soft tissue (extremity and retroperitoneum) are often hyalinized/sclerosed and calcified. However, the prediction of their behavior and correct codification is dependent on thorough, meticulous search for mitoses and necrosis. Leiomyomas of deep soft tissue in the extremity should be devoid of mitoses and "significant" cytological atypia. An occasional larger, slightly pleomorphic cell in the midst of bland spindle cells, can be regarded as insignificant atypia. If any mitotic activity and several atypical cells are encountered in smooth muscle tumors of deep soft tissue of the extremity, it would be prudent to invoke the appellation of smooth muscle tumor of uncertain malignant potential and advocate wide local excision and follow-up.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.