ReviewClinical epidemiology2018
Is dementia incidence declining in high-income countries? A systematic review and meta-analysis.
Review in Clinical epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed.
- Recruitment and Baseline Characteristics of Participants in the AgeWell.de Study-A Pragmatic Cluster-Randomized Controlled Lifestyle Trial against Cognitive Decline.International journal of environmental research and public health · 2021Trial
- Trends in physical and mental health needs across generations in Australia.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Has Increased Medicaid Spending on Home- and Community-Based Services Reduced Unmet Needs in Activities of Daily Living Care among Community-Dwelling Older Adults with Dementia? Evidence from 2008 to 2020.Journal of the American Medical Directors Association · 2025Article
- Decline in Incidence and Prevalence of Dementia: An Analysis of Outpatient Claims Data.Deutsches Arzteblatt international · 2025Observational
- Generational Differences in Age-Specific Dementia Prevalence Rates.JAMA network open · 2025Article
- A clinician implementation protocol for BetterBrains: An online, person-centred risk factor management program to prevent cognitive decline.Australasian journal on ageing · 2025Article
- Addressing common biases in the evaluation of lifetime alcohol consumption patterns and dementia risk: the EPIC-Spain dementia cohort.Frontiers in nutrition · 2025Article
- Education and Adult Cognition in a Low-Income Setting: Differences among Adult Siblings.Journal of human capital · 2025Article
- From dementia prevention research to global FINGER-based multi-domain interventions and implementation strategies.Cerebral circulation - cognition and behavior · 2025Review
- Global health 2050: the path to halving premature death by mid-century.Lancet (London, England) · 2024Review
- The Dual Role of Amyloid Beta-Peptide in Oxidative Stress and Inflammation: Unveiling Their Connections in Alzheimer's Disease Etiopathology.Antioxidants (Basel, Switzerland) · 2024Review
- Projection for dementia burden in China to 2050: a macro-simulation study by scenarios of dementia incidence trends.The Lancet regional health. Western Pacific · 2024Article
- Charting Alzheimer's Disease and Dementia: Epidemiological Insights, Risk Factors and Prevention Pathways.Journal of clinical medicine · 2024Review
- Investigating the individual and joint effects of socioeconomic status and lifestyle factors on mild cognitive impairment in older Italians living independently in the community: results from the NutBrain study.The journal of nutrition, health & aging · 2024Observational
- Global burden of young-onset Alzheimer's disease and other dementias: a secondary analysis of the global burden of disease study, 2019.Dementia & neuropsychologia · 2024Article
- Nutrition, Exercise, and Cognitive Rehabilitation for Dementia Prevention.Juntendo Iji zasshi = Juntendo medical journal · 2024Review
- Dementia incidence trend in England and Wales, 2002-19, and projection for dementia burden to 2040: analysis of data from the English Longitudinal Study of Ageing.The Lancet. Public health · 2023Article
- Prevalence of dementia among older age people and variation across different sociodemographic characteristics: a cross-sectional study in Bangladesh.The Lancet regional health. Southeast Asia · 2023Article
- New cases of dementia are rising in elderly populations in Wales, UK.Journal of the neurological sciences · 2023Article
- Unraveling Lifelong Brain Morphometric Dynamics: A Protocol for Systematic Review and Meta-Analysis in Healthy Neurodevelopment and Ageing.Biomedicines · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo perform a systematic review and quantitative synthesis of studies on recent trends in dementia incidence in high-income countries (HIC), considering study quality.
methodsPubMed and Web of Science were searched for eligible studies, that is, population-based/community-based prospective cohort studies investigating dementia incidence with similar methods over time, published after 1990. Study selection, data extraction, and quality assessment were performed independently by two investigators. Random-effect meta-analysis and meta-regression were used to estimate incidence change (IC) and to explore associations with study attributes. PRISMA standards were followed.
resultsThe systematic review included seven studies (42,485 individuals), and the meta-analysis included five studies of sufficient quality. Relating dementia incidence of later cohorts to earlier cohorts (reference) yielded a nonsignificant decrease across HIC (IC =0.82; 95% CI 0.51-1.33), with high heterogeneity (
conclusionThere is evidence of favorable trends in dementia incidence in Western HIC (stabilizing/decreasing). Reverse trends may occur in HIC of other regions, as exemplified by Japan. However, study number was small and heterogeneity was high. Further cohort studies using consistent methods are needed to draw definite conclusions. Our work may inform such future studies.
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