Evidence map›Paper›PMID 30271150›Full record

ArticleInternational journal of nanomedicine2018

The epigenetic mechanisms of nanotopography-guided osteogenic differentiation of mesenchymal stem cells via high-throughput transcriptome sequencing.

Longwei Lv, Yunsong Liu, Ping Zhang, Xiangsong Bai, Xiaohan Ma, Yuejun Wang, Hongyi Li, Li Wang, Yongsheng Zhou

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Discovering the nucleus in a world of biomaterials.Biomaterials and biosystems · 2024
    Article
  4. Article
  5. Article
  6. 3D-printed polyether-ether-ketone/n-TiOOpen medicine (Warsaw, Poland) · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Anodic TiONanomaterials (Basel, Switzerland) · 2021
    Review
  11. [The Role of Histone Demethylase in Osteogenic and Chondrogenic Differentiation of Mesenchymal Stem Cells: A Literature Review].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Longwei LvDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Disease, Beijing Key Laboratory of Digital Stomatology, Beijing, People's Republic of China, kqzhouysh@hsc.pku.edu.cn.
Yunsong LiuDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Disease, Beijing Key Laboratory of Digital Stomatology, Beijing, People's Republic of China, kqzhouysh@hsc.pku.edu.cn.
Ping ZhangDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Disease, Beijing Key Laboratory of Digital Stomatology, Beijing, People's Republic of China, kqzhouysh@hsc.pku.edu.cn.
Xiangsong BaiDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Disease, Beijing Key Laboratory of Digital Stomatology, Beijing, People's Republic of China, kqzhouysh@hsc.pku.edu.cn.
Xiaohan MaDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Disease, Beijing Key Laboratory of Digital Stomatology, Beijing, People's Republic of China, kqzhouysh@hsc.pku.edu.cn.
Yuejun WangDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Disease, Beijing Key Laboratory of Digital Stomatology, Beijing, People's Republic of China, kqzhouysh@hsc.pku.edu.cn.
Hongyi LiThe key Laboratory of Advanced Functional Materials, Ministry of Education of China, College of Materials Science and Engineering, Beijing University of Technology, Beijing 100124, China.
Li WangState Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, People's Republic of China, wangl@pumc.edu.com.
Yongsheng ZhouDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Disease, Beijing Key Laboratory of Digital Stomatology, Beijing, People's Republic of China, kqzhouysh@hsc.pku.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNanotopography directs stem cell fate; however, the underlying mechanisms, especially those at the epigenetic level, remain vague. The TiO

methodsWe used RNA sequencing and bioinformatics to reveal the overall gene expression profile of hASCs on TiO

resultsBioinformatics analyses revealed that the epigenetic regulatory network plays an important role in TiO

conclusionUsing next-generation sequencing, we illustrated the overall picture of the regulatory mechanisms of TiO

Indexed as

Cell DifferentiationEpigenesis, GeneticOsteogenesisTranscriptomeAdipose TissueCell AdhesionCells, CulturedHigh-Throughput Nucleotide SequencingHumansMesenchymal Stem CellsMicroRNAsNanotubesRNA, Long NoncodingTissue EngineeringMicroRNAsRNA, Long Noncodingepigeneticshistone modificationnon-coding RNAosteogenic differentiationRNA sequencingTiO2 nanotubes

Identifiers

PMID30271150
PMCPMC6154708

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.