ArticleDevelopmental review : DR2018
Rapid Infant Prefrontal Cortex Development and Sensitivity to Early Environmental Experience.
Article in Developmental review : DR, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
84 citing papers in PubMed.
- Mother-infant stress contagion? Effects of an acute maternal stressor on maternal caregiving behavior and infant cortisol and crying.Journal of child psychology and psychiatry, and allied disciplines · 2025Trial
- Creative music therapy to promote brain function and brain structure in preterm infants: A randomized controlled pilot study.NeuroImage. Clinical · 2020Trial
- Promoting toddlers' self-regulation and healthy eating habits among families living in poverty: A randomized controlled trial of Recipe 4 Success.Child developmentTrial
- Type and developmental timing of childhood adversity predicts psychopathology symptoms in a South African birth cohort.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Article
- Evaluation of fetal frontal lobe development and Evans index in pregnancies complicated by gestational diabetes mellitus: prospective comparative observational study.BMC pregnancy and childbirth · 2026Observational
- Development of Interactional Synchrony: Examining the Role of Maternal Emotion Dysregulation.Behavioral sciences (Basel, Switzerland) · 2026Article
- Dietary phytoestrogen ameliorates ovarian toxicant-induced neurotoxicity: mechanistic and metabolic insights.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Developing a Music-Based Mobile Health Intervention for Parents and Staff in Neonatal Care and Beyond: Online Focus Group Study.JMIR pediatrics and parenting · 2026Article
- Executive functioning in the first 24 months: A scoping review of the A-not-B task.Psychological research · 2026Article
- Physical Activity and the Development of Self-Regulation in Early Childhood: A Systematic Review and Meta-Analysis.Journal of Intelligence · 2026Review
- Early-life gastrointestinal inflammation and the developing brain: Unravelling the pathways to long-term cognitive dysfunction.World journal of clinical pediatrics · 2026Review
- Dynamics of infant white matter maturation from birth to 6 months.Communications biology · 2026Article
- Disrupted Development of the mPFC-Thalamic Circuit in Shank3Molecular psychiatry · 2026Article
- Associations of Maternal Pre-Pregnancy BMI With Frontostriatal Connectivity in Young Children.Pediatric obesity · 2026Article
- Dual-axis myelination covariance drives the functional connectivity emergence during infancy.Nature communications · 2026Article
- Screen exposure before age two and developmental outcomes in early childhood: a national cross-sectional study in China.BMC public health · 2026Article
- Hierarchical maturation of structural brain connectomes from birth to childhood.Nature communications · 2026Article
- The relationship between infant feeding types, gut microbiome, intestinal inflammation, and neurodevelopment in a neonatal piglet model.JPEN. Journal of parenteral and enteral nutrition · 2026Article
- Neonatal pain experience and pain sensitivity trajectories in preterm infants: A longitudinal study of flexion withdrawal reflex thresholds over the first two years of age.The journal of pain · 2025Article
24 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Over the last fifteen years, the emerging field of developmental cognitive neuroscience has described the relatively late development of prefrontal cortex in children and the relation between gradual structural changes and children's protracted development of prefrontal-dependent skills. Widespread recognition by the broader scientific community of the extended development of prefrontal cortex has led to the overwhelming perception of prefrontal cortex as a "late developing" region of the brain. However, despite its supposedly protracted development, multiple lines of research have converged to suggest that prefrontal cortex development may be particularly susceptible to individual differences in children's early environments. Recent studies demonstrate that the impacts of early adverse environments on prefrontal cortex are present very early in development: within the first year of life. This review provides a comprehensive overview of new neuroimaging evidence demonstrating that prefrontal cortex should be characterized as a "rapidly developing" region of the brain, discusses the converging impacts of early adversity on prefrontal circuits, and presents potential mechanisms via which adverse environments shape both concurrent and long-term measures of prefrontal cortex development. Given that environmentally-induced disparities are present in prefrontal cortex development within the first year of life, translational work in intervention and/or prevention science should focus on intervening early in development to take advantages of this early period of rapid prefrontal development and heightened plasticity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.