ReviewTropical medicine and infectious disease2017
Four Thousand Years of Concepts Relating to Rabies in Animals and Humans, Its Prevention and Its Cure.
Review in Tropical medicine and infectious disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 131 citations in OpenAlex.
- Safety and Immunogenicity of a novel three-dose recombinant nanoparticle rabies G protein vaccine administered as simulated post exposure immunization: A randomized, comparator controlled, multicenter, phase III clinical study.Human vaccines & immunotherapeutics · 2021Trial
- Rabies: A Timeless Zoonotic Threat.Infectious diseases & clinical microbiology · 2026Article
- Management of Severe Pediatric Lower Lip Defect After Canine Bite with Polyhexamethylene Biguanide (PHMB), Full-Thickness Skin Graft (FTSG) and Compression Foam: A Case Report.Children (Basel, Switzerland) · 2025Article
- The Economic Landscape of Global Rabies: A Scoping Review and Future Directions.Tropical medicine and infectious disease · 2025Review
- The Challenge of Lyssavirus Infections in Domestic and Other Animals: A Mix of Virological Confusion, Consternation, Chagrin, and Curiosity.Pathogens (Basel, Switzerland) · 2025Review
- Social Perceptions and Attitudes Towards Free-Roaming Cats and Dogs in Portugal: An Exploratory Study.Animals : an open access journal from MDPI · 2025Article
- Prevalence and risk factors of rabies in Côte d'Ivoire from 2020 to 2023.Open veterinary journal · 2025Article
- Immunological findings of West Caucasian bat virus in an accidental host.Journal of virology · 2025Article
- Assessment of sexual dimorphismbioRxiv : the preprint server for biology · 2025Article
- Dimerization of Rabies Virus Phosphoprotein and Phosphorylation of Its Nucleoprotein Enhance Their Binding Affinity.Viruses · 2024Article
- Human Rabies Treatment-From Palliation to Promise.Viruses · 2024Review
- Article
- Article
- Tracking lethal threat: in-depth review of rabies.Open veterinary journal · 2023Review
- Article
- Article
- Assessment of Immune Responses to Rabies Vaccination in Free-Ranging Dogs in Bengaluru, India.Vaccines · 2023Article
- Progress towards dog-mediated rabies elimination in PR China: a scoping review.Infectious diseases of poverty · 2023Article
- Detection of immunity in sheep following anti-rabies vaccination.Clinical and experimental vaccine research · 2023Article
- Rabies in a postpandemic world: resilient reservoirs, redoubtable riposte, recurrent roadblocks, and resolute recidivism.Animal diseases · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The epitome of the One Health paradigm-and of its shortcomings-rabies has been known to humankind for at least 4000 years. We review the evolution through history of concepts leading to our current understanding of rabies in dogs and humans and its prevention, as transmitted by accessible and surviving written texts. The tools and concepts currently available to control rabies were developed at the end of the 19th Century, including the first live, attenuated vaccine ever developed for humans and the first post-exposure prophylaxis (PEP) regimen. No progress, however, has been made in etiological treatment, leaving clinicians who provide care to animals or patients with symptomatic rabies as powerless today as their colleagues in Mesopotamia, 40 centuries ago. Rabies remains to date the most lethal infectious disease known to humans. Widespread access to timely, effective, and affordable PEP in rural areas of developing countries is urgently needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.