Evidence map›Paper›PMID 30270683›Full record

ArticleJournal of mental health (Abingdon, England)2019

Prevalence and factors associated with antenatal depressive symptoms among women enrolled in Option B+ antenatal HIV care in Malawi: a cross-sectional analysis.

Bryna J Harrington, Brian W Pence, Mathias John, Caroline G Melhado, Jacob Phulusa, Bryan Mthiko, Bradley N Gaynes, Joanna Maselko, William C Miller, Mina C Hosseinipour

Abstract read
In one paragraph

Article in Journal of mental health (Abingdon, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Review
  7. Observational
  8. Systematic review on the prevalence of perinatal depression in Malawi.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2022
    Article
  9. Prevalence and associated factors of intimate partner violence amongst women attending prevention of mother to child transmission services in Blantyre, Malawi.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bryna J Harringtona Department of Epidemiology , University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.
Brian W Pencea Department of Epidemiology , University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.
Mathias Johnb Project Malawi, University of North Carolina , Lilongwe , Malawi , and.
Caroline G Melhadob Project Malawi, University of North Carolina , Lilongwe , Malawi , and.
Jacob Phulusab Project Malawi, University of North Carolina , Lilongwe , Malawi , and.
Bryan Mthikob Project Malawi, University of North Carolina , Lilongwe , Malawi , and.
Bradley N Gaynesa Department of Epidemiology , University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.
Joanna Maselkoa Department of Epidemiology , University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.
William C Millerc College of Public Health , The Ohio State University , Columbus , OH , USA.
Mina C Hosseinipoura Department of Epidemiology , University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008719 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DARVILLE, TONI, DESHMUKH, MOHANISH P · 1999 to 2023
$15.1M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Fogarty Global Health Fellows Coordinating CenterR25TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2012 to 2016
$6.9M
Option B+: ART Safety and Durability during First and Subsequent PregnanciesR01HD080485 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HOSSEINIPOUR, MINA CHRISTINE · 2014 to 2019
$3.9M
Perinatal depression and key care outcomes in pregnant Malawian women with HIVF30MH111370 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRINGTON, BRYNA · 2016 to 2019
$130k
FIC NIH HHS R25 TW009340NICHD NIH HHS P2C HD050924NICHD NIH HHS R01 HD080485NIGMS NIH HHS T32 GM008719NIMH NIH HHS F30 MH111370
6 · The paper itself

Abstract

backgroundOption B+ has increased the number of pregnant women initiating antiretroviral therapy for HIV, yet retention in HIV care is sub-optimal. Retention may be affected by antenatal depression. However, few data exist on antenatal depression in this population.

aimDescribe the prevalence and factors associated with antenatal depression among Malawian women enrolled in Option B+.

methodAt their first antenatal visit, women with HIV provided demographic and psychosocial information, including depression as measured with the locally validated Edinburgh Postnatal Depression Scale (EPDS). Prevalence ratios (PR) for factors associated with probable depression (EPDS ≥6) were estimated with log binomial regression.

results9.5% (95% CI: 7.5-11.9%) of women screened positive for current depression, and 46% self-reported a history of depression or anxiety. Women were more likely to screen positive for current depression if they reported a history of depression (adjusted PR: 2.42; 95% CI: 1.48-3.95) or had ever experienced intimate partner violence (1.77; 1.11-2.81). Having an unintended current pregnancy (1.78; 0.99-3.21), being unmarried (1.66; 0.97-2.84), or employed (1.56; 1.00-2.44) had potential associations with probable depression.

conclusionsProbable antenatal depression affected a notable proportion of women living with HIV, comparable to other global regions. Screening for antenatal depression in HIV care should be considered.

Indexed as

AdultCross-Sectional StudiesDepressionFemaleHIV InfectionsHumansMalawiPregnancyPregnancy ComplicationsPrenatal CarePrevalencePsychiatric Status Rating ScalesYoung AdultAntenatal depressionHIVOption B+sub-Saharan Africa

Identifiers

PMID30270683
PMCPMC6440874

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.