Evidence map›Paper›PMID 30270492›Full record

ArticlePediatric blood & cancer2019

Defining an optimal time window to screen for hepatoblastoma in children with Beckwith-Wiedemann syndrome.

Alessandro Mussa, Kelly A Duffy, Diana Carli, Giovanni Battista Ferrero, Jennifer M Kalish

Open access · greenAbstract read
In one paragraph

Article in Pediatric blood & cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Update on Surveillance for Wilms Tumor and Hepatoblastoma in Beckwith-Wiedemann Syndrome and Other Predisposition Syndromes.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Hepatoblastoma in molecularly defined, congenital diseases.American journal of medical genetics. Part A · 2022
    Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Syndromic Disorders Caused by Disturbed Human ImprintingJournal of clinical research in pediatric endocrinology · 2020
    Review
  16. The effectiveness of Wilms tumor screening in Beckwith-Wiedemann spectrum.Journal of cancer research and clinical oncology · 2019
    Article
  17. Characterization of the Beckwith-Wiedemann spectrum: Diagnosis and management.American journal of medical genetics. Part C, Seminars in medical genetics · 2019
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Alessandro MussaNeonatal Intensive Care Unit, Department of Obstetrics and Gynecology, Città della Salute e della Scienza di Torino, Torino, Italy.ORCID 0000-0003-2795-6013
Kelly A DuffyDivision of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Diana CarliDepartment of Public Health and Pediatric Sciences, University of Torino, Torino, Italy.
Giovanni Battista FerreroDepartment of Public Health and Pediatric Sciences, University of Torino, Torino, Italy.
Jennifer M KalishDivision of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.ORCID 0000-0003-1500-9713
Children's Hospital of Philadelphia · USAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · IT

Funding

The Mechanism of Tumor Formation in Beckwith-Wiedemann SyndromeK08CA193915 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI KALISH, JENNIFER MELISSA · 2015 to 2019
$703k
NCI NIH HHS K08 CA193915NIH HHS K08CA193915
6 · The paper itself

Abstract

Patients with Beckwith-Wiedemann spectrum (BWSp) undergo quarterly alpha-fetoprotein measurement for hepatoblastoma (HB) screening up to 4 years of age, paralleling the epidemiology of nonsyndromic HB. However, specific data on the timing of HB development in BWSp are lacking. Here we compare the timing of presentation of HBs in BWSp with a control cohort of consecutive HB cases, demonstrating that halving screening duration of screening procedures in BWSp likely will not impact its effectiveness.

Indexed as

alpha-FetoproteinsBeckwith-Wiedemann SyndromeChild, PreschoolEarly Detection of CancerFemaleFollow-Up StudiesHepatoblastomaHumansInfantLiver NeoplasmsMalePrognosisRetrospective StudiesTime Factorsalpha-Fetoproteinsalpha-fetoproteinBeckwith-Wiedemanncancer screeninghepatoblastoma

Identifiers

PMID30270492
PMCPMC7955797
OpenAlexW2895610491

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.