Evidence map›Paper›PMID 30269802›Full record

ReviewPM & R : the journal of injury, function, and rehabilitation2018

Transcranial Direct Current Stimulation for Poststroke Motor Recovery: Challenges and Opportunities.

Wuwei Feng, Steven A Kautz, Gottfried Schlaug, Caitlyn Meinzer, Mark S George, Pratik Y Chhatbar

Abstract readReview
In one paragraph

Review in PM & R : the journal of injury, function, and rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  5. Breaking the ice to improve motor outcomes in patients with chronic stroke: a retrospective clinical study on neuromodulation plus robotics.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wuwei FengDepartments of Neurology and Health Science and Research, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425(∗). Electronic address: feng@musc.edu.
Steven A KautzDepartment of Health Science and Research, Medical University of South Carolina, Charleston; and Ralph H. Johnson VA Medical Center, Charleston, SC(†).
Gottfried SchlaugDepartment of Neurology, Neuroimaging and Stroke Recovery Lab, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA(‡).
Caitlyn MeinzerDepartment of Public Health Science, Medical University of South Carolina, Charleston, SC(§).
Mark S GeorgeDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston; and Ralph H. Johnson VA Medical Center, Charleston, SC(¶).
Pratik Y ChhatbarDepartment of Neurology, Medical University of South Carolina, Charleston, SC(#).

Funding

Treating Depression and Enhancing Locomotor Recovery Post-strokeP20GM109040 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KAUTZ, STEVEN A. · 2014 to 2024
$23.5M
Workshop to Identify Collaborative Project(s) for the NIH StrokeNet and the Japan NEtwork for Clinical Stroke Trials (NECST)U01NS087748 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Catherine R. Dillon, Jordan J. Elm · 2014 to 2026
$14.1M
Techniques DevelopmentP2CHD086844 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI GEORGE, MARK S · 2015 to 2024
$12.7M
TRANScranial direct current stimulation for POst-stroke motor Recover - a phase II sTudy (TRANSPORT 2)U01NS102353 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI FENG, WUWEI, SCHLAUG, GOTTFRIED · 2018 to 2023
$8.5M
Imaging the Neural Effects of Transcranial Direct Current StimulationR01MH111874 · NIMH · UNIVERSITY OF MASSACHUSETTS AMHERST · PI SCHLAUG, GOTTFRIED · 2016 to 2019
$2.2M
South Carolina Collaborative Alliance for Stroke Trials (SC-CoAST)U10NS086490 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI JAUCH, EDWARD C · 2013 to 2017
$1.6M
NICHD NIH HHS P2C HD086844NIGMS NIH HHS P20 GM109040NIMH NIH HHS R01 MH111874NINDS NIH HHS U01 NS087748NINDS NIH HHS U01 NS102353NINDS NIH HHS U10 NS086490RRD VA IK6 RX003075
6 · The paper itself

Abstract

There has been a renewed research interest in transcranial direct current stimulation (tDCS) as an adjunctive tool for poststroke motor recovery as it has a neuro-modulatory effect on the human cortex. However, there are barriers towards its successful application in motor recovery as several scientific issues remain unresolved, including device-related issues (ie, dose-response relationship, safety and tolerability concerns, interhemispheric imbalance model, and choice of montage) and clinical trial-related issues (ie, patient selection, timing of study, and choice of outcomes). This narrative review examines and discusses the existing challenges in using tDCS as a brain modulation tool in facilitating recovery after stroke. Potential solutions pertinent to using tDCS with the goal of harnessing the brains plasticity are proposed.

Indexed as

Recovery of FunctionEvoked Potentials, MotorHumansMotor CortexStroke RehabilitationTranscranial Direct Current Stimulation

Identifiers

PMID30269802
PMCPMC7153501

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.