Evidence map›Paper›PMID 30269683›Full record

SynthesisTrends in hearing

Association Between Subjective Tinnitus and Cervical Spine or Temporomandibular Disorders: A Systematic Review.

E J Bousema, E A Koops, P van Dijk, P U Dijkstra

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Trends in hearing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Otologic Manifestations of Temporomandibular Disorders.Diagnostics (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Tinnitus: Clinical Insights in Its Pathophysiology-A Perspective.Journal of the Association for Research in Otolaryngology : JARO · 2024
    Review
  9. Article
  10. AUDISTIMAudiology research · 2024
    Article
  11. Article
  12. Association of Vitamin D Deficiency in Patients with Tinnitus with Normal Audiogram.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

E J Bousema1 Department of Otorhinolaryngology, Head & Neck Surgery, University Medical Center Groningen, University of Groningen, the Netherlands.ORCID 0000-0002-6819-3078
E A Koops1 Department of Otorhinolaryngology, Head & Neck Surgery, University Medical Center Groningen, University of Groningen, the Netherlands.
P van Dijk1 Department of Otorhinolaryngology, Head & Neck Surgery, University Medical Center Groningen, University of Groningen, the Netherlands.
P U Dijkstra4 Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, the Netherlands.
University Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Movements of the neck and jaw may modulate the loudness and pitch of tinnitus. The aim of the present study was to systematically analyze the strength of associations between subjective tinnitus, cervical spine disorders (CSD), and temporomandibular disorders (TMD). A systematic literature search of the Medline, Embase, and Pedro databases was carried out on articles published up to September 2017. This covered studies in which tinnitus and CSD or TMD were studied as a primary or a secondary outcome and in which outcomes were compared with a control group. Included articles were evaluated on nine methodological quality criteria. Associations between tinnitus and CSD or TMD were expressed as odds ratios. In total, 2,139 articles were identified, of which 24 studies met the inclusion criteria. Twice, two studies were based on the same data set; consequently, 22 studies were included in the meta-analysis. Methodological quality was generally limited by a lack of blinding, comparability of groups, and nonvalidated instruments for assessing CSD. Results indicated that patients with tinnitus more frequently reported CSD than subjects without tinnitus. The odds ratio was 2.6 (95% CI [1.1, 6.4]). For TMD, a bidirectional association with tinnitus was found; odds ratios ranged from 2.3 (95%CI [1.5, 3.6]) for arthrogenous TMD to 6.7 (95%CI [2.4, 18.8]) for unspecified TMD. Funnel plots suggested a publication bias. After adjusting for this, the odds ratios decreased, but associations persisted. There is weak evidence for an association between subjective tinnitus and CSD and a bidirectional association between tinnitus and TMD.

Indexed as

Cervical VertebraeComorbidityFemaleHumansMaleNeck PainOdds RatioPrevalencePrognosisRisk AssessmentSeverity of Illness IndexTemporomandibular Joint DisordersTinnitusneck painsubjective tinnitussystematic reviewtemporomandibular disorder

Identifiers

PMID30269683
PMCPMC6168723
OpenAlexW2895363127

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.