Evidence map›Paper›PMID 30269676›Full record

ArticleRNA biology2018

Identification of factors that promote biogenesis of tRNA

Fu Xu, Yang Zhou, Anders S Byström, Marcus J O Johansson

Open access · bronzeAbstract read
In one paragraph

Article in RNA biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. New reporters for monitoring cellular NMD.RNA (New York, N.Y.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Fu Xua Department of Molecular Biology , Umeå University , Umeå , Sweden.
Yang Zhoua Department of Molecular Biology , Umeå University , Umeå , Sweden.
Anders S Byströma Department of Molecular Biology , Umeå University , Umeå , Sweden.
Marcus J O Johanssona Department of Molecular Biology , Umeå University , Umeå , Sweden.ORCID 0000-0001-7117-7426
Umeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A wide variety of factors are required for the conversion of pre-tRNA molecules into the mature tRNAs that function in translation. To identify factors influencing tRNA biogenesis, we previously performed a screen for strains carrying mutations that induce lethality when combined with a sup61-T47:2C allele, encoding a mutant form of [Formula: see text]. Analyzes of two complementation groups led to the identification of Tan1 as a protein involved in formation of the modified nucleoside N

Indexed as

Protein BiosynthesisAdenosine TriphosphatasesAlkyl and Aryl TransferasesCarrier ProteinsMutationNuclear Pore Complex ProteinsOxidoreductasesPol1 Transcription Initiation Complex ProteinsRNA PrecursorsRNA, TransferSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTATA-Binding Protein Associated FactorstRNA MethyltransferasesAdenosine TriphosphatasesAlkyl and Aryl TransferasesBud13 protein, S cerevisiaeCarrier ProteinsLos1 protein, S cerevisiaeMOD5 protein, S cerevisiaeMOT1 protein, S cerevisiaeN(2),N(2)-dimethylguanosine-26-methyltransferaseNuclear Pore Complex ProteinsOxidoreductasesPol1 Transcription Initiation Complex ProteinsRNA PrecursorsRNA, TransferRRN3 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsSMM1 protein, S cerevisiaeTATA-Binding Protein Associated FactorstRNA Methyltransferasesmodified nucleosidessup61tRNA maturationtRNA modificationtRNASer

Identifiers

PMID30269676
PMCPMC6284589
OpenAlexW2892785222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.