ReviewWorld journal of pediatrics : WJP2018
Erythema nodosum.
Review in World journal of pediatrics : WJP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 82 citations in OpenAlex.
- Unexpected erythema nodosum during dupilumab treatment for severe asthma: Causal or casual?JAAD case reports · 2026Article
- Celiac Disease Presenting With Erythema Nodosum in a Child: Case Report and Review of the Literature.Case reports in pediatrics · 2026Article
- Erythema Nodosum as the Primary Manifestation of Acute Histoplasmosis in a Pediatric Patient From an Endemic Region.Cureus · 2025Article
- The causal impact of genetically predicted inflammatory bowel disease on extraintestinal manifestations: a mendelian randomization study.BMC gastroenterology · 2025Article
- [Erythema nodosum].Dermatologie (Heidelberg, Germany) · 2025Article
- Risk Factors Analysis of Cutaneous Adverse Drug Reactions Caused by Targeted Therapy and Immunotherapy Drugs for Oncology and Establishment of a Prediction Model.Clinical and translational science · 2025Article
- Association between inflammatory bowel disease and erythema nodosum: a two-sample mendelian randomization study.Archives of dermatological research · 2024Article
- Exploring the connection between hidradenitis suppurativa and erythema nodosum: a case report.Dermatology reports · 2024Article
- [Erythema nodosum].Zeitschrift fur Rheumatologie · 2024Article
- The causal relationship between inflammatory bowel diseases and erythema nodosum: a bidirectional two-sample mendelian randomization study.BMC gastroenterology · 2024Article
- Erythema nodosum in northern Finland between 1996 and 2019: A register-based study.The Journal of dermatology · 2024Article
- Article
- Case Report: Melioidosis-Related Severe Cutaneous Features of Erythema Nodosum in a Thai Child.The American journal of tropical medicine and hygiene · 2024Article
- Article
- Yersinia enterocolitica Enteritis Diagnosed with Erythema Nodosum.Internal medicine (Tokyo, Japan) · 2023Article
- Erythema nodosum in children: a cohort study from a tertiary pediatric hospital in Italy.European journal of pediatrics · 2023Observational
- Cutaneous manifestations of inflammatory bowel disease: basic characteristics, therapy, and potential pathophysiological associations.Frontiers in immunology · 2023Review
- [Granulomatous dermatoses].Zeitschrift fur Rheumatologie · 2022Review
- Immune-Related Uncommon Adverse Events in Patients with Cancer Treated with Immunotherapy.Diagnostics (Basel, Switzerland) · 2022Review
- Autoimmune Disease Classification Based on PubMed Text Mining.Journal of clinical medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundErythema nodosum can be associated with a number of systemic diseases. There is, however, a paucity of information in the pediatric literature on this condition. The purpose of this article is to familiarize pediatricians with the evaluation, diagnosis, and treatment of erythema nodosum. DATA SOURCES: A PubMed search was completed in Clinical Queries using the key terms "erythema nodosum".
resultsClinically, erythema nodosum presents with a sudden onset of painful, erythematous, subcutaneous nodules mainly localized to the pretibial areas. Lesions are usually bilateral and symmetrical, ranging from 1 to 5 cm in diameter. Erythema nodosum may be associated with a variety of conditions such as infection, medications, sarcoidosis, pregnancy, inflammatory bowel disease, vaccination, autoimmune disease, malignancy, and miscellaneous causes. The condition is idiopathic in approximately 50% of cases. The diagnosis is mainly clinical with biopsy reserved for atypical cases. To evaluate for the underlying cause, some basic laboratory screening studies are worthwhile in most cases and include a complete blood cell count, erythrocyte sedimentation rate and/or C-reactive protein, throat swab culture, antistreptococcal O titers, and a chest radiograph. Other tests should be individualized, guided by the history and physical examination results. Most cases of erythema nodosum are self-limited and require no treatment. Bed rest and leg elevation are generally recommended to reduce the discomfort. Nonsteroidal anti-inflammatory drugs are the first-line treatment for pain management.
conclusionsAs erythema nodosum is often a cutaneous manifestation of a systemic disease, a thorough search should be performed to reveal the underlying cause.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.