Evidence map›Paper›PMID 30269233›Full record

ArticleAIDS and behavior2019

Engagement in Maximally-Assisted Therapy and Adherence to Antiretroviral Therapy Among a Cohort of Indigenous People Who Use Illicit Drugs.

Brittany Barker, Evan Adams, Evan Wood, Thomas Kerr, Kora DeBeck, Huiru Dong, Jean Shoveller, Julio Montaner, M-J Milloy

Open access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Implementation of Low-Barrier Human Immunodeficiency Virus Care: Lessons Learned From the Max Clinic in Seattle.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Brittany BarkerBritish Columbia Centre on Substance Use, Vancouver, Canada.
Evan AdamsFirst Nations Health Authority, BC Provincial Government, Vancouver, Canada.
Evan WoodBritish Columbia Centre on Substance Use, Vancouver, Canada.
Thomas KerrBritish Columbia Centre on Substance Use, Vancouver, Canada.
Kora DeBeckBritish Columbia Centre on Substance Use, Vancouver, Canada.
Huiru DongBritish Columbia Centre on Substance Use, Vancouver, Canada.
Jean ShovellerSchool of Population and Public Health, University of British Columbia, Vancouver, Canada.
Julio MontanerBritish Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada.
M-J MilloyBritish Columbia Centre on Substance Use, Vancouver, Canada. bccsu-mjsm@bccsu.ubc.ca.ORCID http://orcid.org/0000-0003-3821-6221
University of British Columbia · CAAIDS Vancouver · CASimon Fraser University · CA

Funding

Impacts of universal access to HIV/AIDS care among HIV+ injection drug usersU01DA021525 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI MILLOY, M-J · 2017 to 2024
$4.3M
Seek and Treat for Optimal Outcomes and Prevention in HIV & AIDS in IDUDP1DA026182 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MONTANER, JULIO SERGIO GONZALEZ · 2008 to 2013
$3.9M
National Institutes of Health U01-DA021525NIDA NIH HHS DP1 DA026182NIDA NIH HHS U01 DA021525
6 · The paper itself

Abstract

Throughout the world, Indigenous populations experience a disproportionate burden of HIV infection. Maximally-assisted therapy (MAT) is an interdisciplinary care intervention that includes ART dispensation to support individuals with a history of addiction and homelessness. This study sought to longitudinally evaluate the relationship between engagement in MAT and achieving optimal adherence using data from an ongoing cohort of HIV-positive individuals who use drugs in Vancouver, Canada, where HIV/AIDS treatment is offered at no cost. Between December 2005 and November 2016, 354 HIV-positive Indigenous participants were enrolled and data were analyzed using generalized mixed-effects (GLMM) and marginal structural modeling. In both multivariable analyses, engagement in MAT was independently associated with optimal adherence to ART (GLMM: AOR = 4.92, 95% CI 3.18-7.62; marginal structural model: AOR = 5.76, 95% CI 3.34-9.96). MAT-based programmes could be a part of a renewed evidence-base to elevated levels of preventable HIV/AIDS-associated morbidity, mortality and viral transmission among Indigenous peoples in Canada.

Indexed as

Drug MonitoringIllicit DrugsPopulation GroupsAdultCanadaDrug UsersFemaleHIV InfectionsHumansLongitudinal StudiesMalePatient ParticipationIllicit DrugsAntiretroviral therapyCanadaHIVHIV interventionsIndigenous peoplePeople who use drugs

Identifiers

PMID30269233
PMCPMC6440861
OpenAlexW2892754548

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.