Evidence map›Paper›PMID 30269158›Full record

ArticleImmunogenetics2019

A genome-wide association study for mastitis resistance in phenotypically well-characterized Holstein dairy cattle using a selective genotyping approach.

Jacqueline P Kurz, Zhou Yang, Robert B Weiss, David J Wilson, Kerry A Rood, George E Liu, Zhongde Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Immunogenetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 62 citations in OpenAlex.

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  5. Sequence variants associated with resilient responses in growing pigs.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Jacqueline P KurzDepartment of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA.
Zhou YangKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Education Ministry of China, Huazhong Agricultural University, Wuhan, 430070, Hubei, China.
Robert B WeissDepartment of Human Genetics, University of Utah, Salt Lake City, UT, USA.
David J WilsonDepartment of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA. david.wilson@usu.edu.
Kerry A RoodDepartment of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA.
George E LiuAnimal Genomics and Improvement Laboratory, BARC, USDA-ARS, Beltsville, MD, USA. george.liu@ars.usda.gov.
Zhongde WangDepartment of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA. zonda.wang@usu.edu.
Utah State University · USAgricultural Research Service · USHuazhong Agricultural University · CNUniversity of Utah · US

Funding

From genomics to natural language processing: A protected environment for research computing in the health scienceS10OD021644 · OD · UNIVERSITY OF UTAH · PI CHEATHAM, THOMAS E. · 2017 to 2017
$494k
NIH HHS S10 OD021644
6 · The paper itself

Abstract

A decrease in the incidence of bovine mastitis, the costliest disease in the dairy industry, can be facilitated through genetic marker-assisted selective breeding programs. Identification of genomic variants associated with mastitis resistance is an ongoing endeavor for which genome-wide association studies (GWAS) using high-density arrays provide a valuable tool. We identified single nucleotide polymorphisms (SNPs) in Holstein dairy cattle associated with mastitis resistance in a GWAS by using a high-density SNP array. Mastitis-resistant (15) and mastitis-susceptible (28) phenotypic extremes were identified from 224 lactating dairy cows on commercial dairy farm located in Utah based on multiple criteria of mastitis resistance over an 8-month period. Twenty-seven quantitative trait loci (QTLs) for mastitis resistance were identified based on 117 SNPs suggestive of genome-wide significance for mastitis resistance (p ≤ 1 × 10

Indexed as

Genome-Wide Association StudyGenotyping TechniquesAnimalsCattleFemaleMastitis, BovinePhenotypePolymorphism, Single NucleotideQuantitative Trait Lociras-GRF1ras-GRF1Bovine mastitis resistanceCattleGenome-wide association studySelective genotyping

Identifiers

PMID30269158
OpenAlexW2893053176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.