Evidence map›Paper›PMID 30269154›Full record

ReviewEuropean journal of nuclear medicine and molecular imaging2019

Dynamic whole-body PET imaging: principles, potentials and applications.

Arman Rahmim, Martin A Lodge, Nicolas A Karakatsanis, Vladimir Y Panin, Yun Zhou, Alan McMillan, Steve Cho, Habib Zaidi, Michael E Casey, Richard L Wahl

Abstract readReview
PubMed Publisher
In one paragraph

Review in European journal of nuclear medicine and molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
144citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

144 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Non-invasive kinetic modelling approaches for quantitative analysis of brain PET studies.European journal of nuclear medicine and molecular imaging · 2023
    Pooled it
  2. Article
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  5. Impact of biguanide therapy on hepaticAnnals of nuclear medicine · 2026
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  7. Mitigating bladder signal inEJNMMI physics · 2026
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  9. Article
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  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Total Body PET.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  18. Current Uses for Medical Imaging With Orthopaedic Implant Technology.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Review
  19. Article
  20. Review

84 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Arman RahmimDepartment of Radiology and Radiological Science, Johns Hopkins University, JHOC Building Room 3245, 601 N. Caroline St, Baltimore, MD, 21287, USA. arahmim1@jhmi.edu.ORCID 0000-0002-9980-2403
Martin A LodgeDepartment of Radiology and Radiological Science, Johns Hopkins University, JHOC Building Room 3245, 601 N. Caroline St, Baltimore, MD, 21287, USA.
Nicolas A KarakatsanisDepartment of Radiology, Weill Cornell Medical College, New York, NY, USA.
Vladimir Y PaninSiemens Healthineers, Knoxville, TN, 37932, USA.
Yun ZhouDepartment of Radiology and Radiological Science, Johns Hopkins University, JHOC Building Room 3245, 601 N. Caroline St, Baltimore, MD, 21287, USA.
Alan McMillanDepartment of Radiology, University of Wisconsin, Madison, WI, 53705, USA.
Steve ChoDepartment of Radiology, University of Wisconsin, Madison, WI, 53705, USA.
Habib ZaidiDivision of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva, Switzerland.
Michael E CaseySiemens Healthineers, Knoxville, TN, 37932, USA.
Richard L WahlMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.

Funding

Swiss National Science Foundation SNSF 320030_176052
6 · The paper itself

Abstract

purposeIn this article, we discuss dynamic whole-body (DWB) positron emission tomography (PET) as an imaging tool with significant clinical potential, in relation to conventional standard uptake value (SUV) imaging.

backgroundDWB PET involves dynamic data acquisition over an extended axial range, capturing tracer kinetic information that is not available with conventional static acquisition protocols. The method can be performed within reasonable clinical imaging times, and enables generation of multiple types of PET images with complementary information in a single imaging session. Importantly, DWB PET can be used to produce multi-parametric images of (i) Patlak slope (influx rate) and (ii) intercept (referred to sometimes as "distribution volume"), while also providing (iii) a conventional 'SUV-equivalent' image for certain protocols.

resultsWe provide an overview of ongoing efforts (primarily focused on FDG PET) and discuss potential clinically relevant applications.

conclusionOverall, the framework of DWB imaging [applicable to both PET/CT(computed tomography) and PET/MRI (magnetic resonance imaging)] generates quantitative measures that may add significant value to conventional SUV image-derived measures, with limited pitfalls as we also discuss in this work.

Indexed as

HumansImage Processing, Computer-AssistedPositron-Emission TomographySignal-To-Noise RatioWhole Body ImagingDynamicKinetic modelingParametric imagingPETSystemic diseaseWhole-body

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.