Evidence map›Paper›PMID 30269056›Full record

ArticleJournal of epidemiology and community health2019

Neighbourhood racial/ethnic residential segregation and cardiometabolic risk: the multiethnic study of atherosclerosis.

Stephanie L Mayne, Margaret T Hicken, Sharon Stein Merkin, Teresa E Seeman, Kiarri N Kershaw, D Phuong Do, Anjum Hajat, Ana V Diez Roux

Abstract readMulticenter Study
In one paragraph

Article in Journal of epidemiology and community health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. State-Level Structural Racism and Incident Coronary Heart Disease.Journal of the American Heart Association · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Measuring Spatial Social Polarization in Public Health Research: A Scoping Review of Methods and Applications.Journal of urban health : bulletin of the New York Academy of Medicine · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. "Moving on Up? Neighborhood Status and Racism-Related Distress among Black Americans".Social forces; a scientific medium of social study and interpretation · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Stephanie L MayneDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Margaret T HickenInstitute for Social Research, University of Michigan, Ann Arbor, Michigan, USA.
Sharon Stein MerkinDivision of Geriatrics, Geffen School of Medicine at the University of California Los Angeles, Los Angeles, California, USA.
Teresa E SeemanDivision of Geriatrics, Geffen School of Medicine at the University of California Los Angeles, Los Angeles, California, USA.
Kiarri N KershawDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
D Phuong DoZilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
Anjum HajatDepartment of Epidemiology, University of Washington School of Public Health, Seattle, Washington, USA.
Ana V Diez RouxUrban Health Collaborative, Drexel University Dornsife School of Public Health, Philadelphia, Pennsylvania, USA.
University of California, Los Angeles · USChildren's Hospital of Philadelphia · USDrexel University · USNorthwestern University · USUniversity of Michigan–Ann Arbor · USUniversity of Washington · USUniversity of Wisconsin–Milwaukee · US

Funding

Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI CATHERINE J KARR · 1995 to 2026
$42.5M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Social-biological predictors of heterogeneity in CVD risk in African AmericansP60MD002249 · NIMHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DIEZ ROUX, ANA VICTORIA · 2007 to 2016
$15.0M
RESEARCH TRAINING IN CVD EPIDEMIOLOGY AND PREVENTIONT32HL069771 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Mercedes Renee Carnethon · 2003 to 2026
$5.9M
Neighborhoods and CVD Risk in a Multiethnic Cohort (RMI)R01HL071759 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DIEZ ROUX, ANA VICTORIA · 2003 to 2013
$4.8M
Cigarette Smoke and Susceptibility to Influenza InfectionR01HL095163 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JASPERS, ILONA, NOAH, TERRY L · 2009 to 2013
$2.0M
Adjunctive Use of Apyrase to Fibrinolytic TherapyR44HL095169 · NHLBI · APT THERAPEUTICS, INC. · PI CHEN, RIDONG · 2012 to 2013
$1.3M
SUBCLINICAL CARDIOVASCULAR DISEASE STUDYN01HC095166 · HC · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI TRACY, RUSSELL P · 1999 to 2001
$758k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY-FIELD CENTERN01HC095162 · HC · JOHNS HOPKINS UNIVERSITY · PI SZKLO, MOYSES A · 1999 to 2000
$694k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095161 · HC · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHEA, STEVEN · 1999 to 2001
$642k
NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NCATS NIH HHS UL1 TR001420NHLBI NIH HHS HHSN268201500003CNHLBI NIH HHS HHSN268201500003INHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS R01 HL071759NHLBI NIH HHS T32 HL069771NIEHS NIH HHS P30 ES007033NIMHD NIH HHS P60 MD002249
6 · The paper itself

Abstract

backgroundRacial residential segregation has been linked to adverse health outcomes, but associations may operate through multiple pathways. Prior studies have not examined associations of neighbourhood-level racial segregation with an index of cardiometabolic risk (CMR) and whether associations differ by race/ethnicity.

methodsWe used data from the Multi-Ethnic Study of Atherosclerosis to estimate cross-sectional and longitudinal associations of baseline neighbourhood-level racial residential segregation with a composite measure of CMR. Participants included 5015 non-Hispanic black, non-Hispanic white and Hispanic participants aged 45-84 years old over 12 years of follow-up (2000-2012). We used linear mixed effects models to estimate race-stratified associations of own-group segregation with CMR at baseline and with the rate of annual change in CMR. Models were adjusted for sociodemographics, medication use and individual-level and neighbourhood-level socioeconomic status (SES).

resultsIn models adjusted for sociodemographics and medication use, high baseline segregation was associated with higher baseline CMR among blacks and Hispanics but lower baseline CMR among whites. Individual and neighbourhood-level SES fully explained observed associations between segregation and CMR for whites and Hispanics. However, associations of segregation with CMR among blacks remained (high vs low segregation: mean difference 0.17 SD units, 95% CI 0.02 to 0.32; medium vs low segregation: mean difference 0.18 SD units, 95% CI 0.03 to 0.33). Baseline segregation was not associated with change in CMR index scores over time.

conclusionAssociations of own-group racial residential segregation with CMR varied by race/ethnicity. After accounting for SES, living in a more segregated neighbourhood was associated with greater risk among black participants only.

Indexed as

RacismResidence CharacteristicsAgedAged, 80 and overAtherosclerosisBlack or African AmericanCross-Sectional StudiesFemaleHealth Status DisparitiesHispanic or LatinoHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesSocioeconomic Factorslongitudinal studiesneighborhood/placesocial epidemiology

Identifiers

PMID30269056
PMCPMC6398328
OpenAlexW2893983645

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.