Evidence map›Paper›PMID 30269002›Full record

Trial reportJournal of anxiety disorders2018

Psychophysiological reactivity, coping behaviour and intrusive memories upon multisensory Virtual Reality and Script-Driven Imagery analogue trauma: A randomised controlled crossover study.

Tina Schweizer, Fritz Renner, Dali Sun, Birgit Kleim, Emily A Holmes, Brunna Tuschen-Caffier

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of anxiety disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Tina SchweizerDepartment of Psychology, Clinical Psychology and Psychotherapy, University of Freiburg, 79085 Freiburg, Germany. Electronic address: tina.schweizer@psychologie.uni-freiburg.de.
Fritz RennerDepartment of Psychology, Clinical Psychology and Psychotherapy, University of Freiburg, 79085 Freiburg, Germany; MRC Cognition and Brain Sciences Unit, University of Cambridge, CB2 7EF Cambridge, United Kingdom.
Dali SunDepartment of Computer Science, University of Freiburg, 79110 Freiburg, Germany.
Birgit KleimDepartment of Experimental Psychopathology and Psychotherapy, University of Zurich, 8050 Zurich, Switzerland; Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, 8032 Zurich, Switzerland.
Emily A HolmesDivision of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, SE-171 65 Solna, Sweden.
Brunna Tuschen-CaffierDepartment of Psychology, Clinical Psychology and Psychotherapy, University of Freiburg, 79085 Freiburg, Germany.
University of Freiburg · DEKarolinska Institutet · SEUniversity of Zurich · CH

Funding

Medical Research Council SUAI/022 RG92024
6 · The paper itself

Abstract

backgroundPeri- and post-traumatic factors predict the differential development of stress-associated mental disorders. Prospective designs assessing these risk factors in real-time under controlled experimental conditions can overcome limitations of retrospective designs. Therefore, we aimed to investigate multi-sensory, experimental analogues of a traumatic experience delivered in Virtual Reality (VR) or Script-Driven Imagery (SDI).

methodsIn a randomised controlled crossover design, differences in the induced analogue trauma symptoms between multi-sensory analogue trauma by either VR or SDI versus a neutral condition were assessed in 127 non-clinical participants.

resultsAnalogue symptoms (psychophysiological responses, coping behaviour and intrusive memories of the experimental trauma) increased following analogue trauma in both VR and SDI, with more analogue symptoms for VR. Psychophysiological arousal was in general higher in VR. LIMITATIONS: The analogue trauma situation of a car park fire that was used may be infrequent in real life.

conclusionsMultisensory (vision, olfaction, hearing) analogue trauma in VR and SDI offers a useful tool for the induction and real-time assessment of peri- and post-traumatic risk factors for analogue stress-associated psychopathology. VR was more effective in inducing analogue symptoms than SDI, even though the latter might be more personalised. New experimental models for studying trauma exposure and responses may contribute to a better understanding of risk factors and help to identify and protect individuals at risk.

Indexed as

Adaptation, PsychologicalImagery, PsychotherapyMemoryPsychophysiologyVirtual RealityArousalCross-Over StudiesFemaleHumansMaleProspective StudiesPsychological TraumaYoung AdultGuided mental imageryPost-traumatic stressPsychopathologyRisk factorsStress and coping measuresVirtual Reality

Identifiers

PMID30269002
PMCPMC6249992
OpenAlexW2886389509

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.