Evidence map›Paper›PMID 30268699›Full record

ArticleExperimental eye research2019

Detection of microvascular retinal changes in type I diabetic mice with optical coherence tomography angiography.

Hironori Uehara, Timilai Lesuma, Parker Stocking, Nathan Jensen, Sangeetha Ravi Kumar, Mingyang Aaron Zhang, Susie Choi, Xiaohui Zhang, Bonnie Archer, Lara Carroll and 1 more

Abstract read
In one paragraph

Article in Experimental eye research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Hironori UeharaDept. of Ophthalmology, Moran Eye Center, University of Utah, 65 Mario Capecchi Dr., Salt Lake City, UT, 84132, United States.
Timilai LesumaDept. of Ophthalmology, Moran Eye Center, University of Utah, 65 Mario Capecchi Dr., Salt Lake City, UT, 84132, United States.
Parker StockingRocky Vista University College of Osteopathic Medicine, 255 E. Center St. Ivins, UT, 84738, United States.
Nathan JensenDept. of Ophthalmology, Moran Eye Center, University of Utah, 65 Mario Capecchi Dr., Salt Lake City, UT, 84132, United States.
Sangeetha Ravi KumarDept. of Ophthalmology, Moran Eye Center, University of Utah, 65 Mario Capecchi Dr., Salt Lake City, UT, 84132, United States.
Mingyang Aaron ZhangDept. of Ophthalmology, Moran Eye Center, University of Utah, 65 Mario Capecchi Dr., Salt Lake City, UT, 84132, United States.
Susie ChoiDept. of Ophthalmology, Moran Eye Center, University of Utah, 65 Mario Capecchi Dr., Salt Lake City, UT, 84132, United States.
Xiaohui ZhangDept. of Ophthalmology, Moran Eye Center, University of Utah, 65 Mario Capecchi Dr., Salt Lake City, UT, 84132, United States.
Bonnie ArcherDept. of Ophthalmology, Moran Eye Center, University of Utah, 65 Mario Capecchi Dr., Salt Lake City, UT, 84132, United States.
Lara CarrollDept. of Ophthalmology, Moran Eye Center, University of Utah, 65 Mario Capecchi Dr., Salt Lake City, UT, 84132, United States.
Balamurali K AmbatiDept. of Ophthalmology, Moran Eye Center, University of Utah, 65 Mario Capecchi Dr., Salt Lake City, UT, 84132, United States. Electronic address: bambati@gmail.com.
University of Utah · USRocky Vista University · US

Funding

COMP-ANG1: VASCULAR NORMALIZATION AND NEUROPROTECTION FOR DIABETIC RETINOPATHYR01EY026029 · NEI · UNIVERSITY OF UTAH · PI AMBATI, BALAMURALI K · 2016 to 2019
$1.3M
NEI NIH HHS R01 EY026029
6 · The paper itself

Abstract

Optical coherence tomography (OCT) angiography is a dye-free and non-invasive angiography which allows visualization of retinal and choroid vascular flow, enabling observation of highly permeable and three dimensional vasculature. Although OCT angiography is providing new insights in human retinal and choroidal diseases, a few studies have been reported in experimental mice. In this study, to determine the potential of OCT angiography in experimental mice, we sought to examine whether OCT angiography can detect vascular change in type I diabetic mice. To conduct age dependent analysis, 2 and 6 month old male type 1 diabetic Ins2

Indexed as

AgingAnimalsDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 1Diabetic RetinopathyFluorescein AngiographyMaleMiceMice, Inbred C57BLMicrovesselsRetinal VesselsTomography, Optical CoherenceMurine diabetic retinopathyOptical coherence tomography angiography

Identifiers

PMID30268699
PMCPMC6361705
OpenAlexW2894506718

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.