Evidence map›Paper›PMID 30268400›Full record

ArticleThe Journal of pediatrics2018

Early Childhood Inpatient Costs of Critical Congenital Heart Disease.

Nelangi M Pinto, Norman Waitzman, Richard Nelson, L LuAnn Minich, Sergey Krikov, Lorenzo D Botto

Abstract read
In one paragraph

Article in The Journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nelangi M PintoDivision of Cardiology, Department of Pediatrics, University of Utah, Salt Lake City, UT. Electronic address: nelangi.pinto@hsc.utah.edu.
Norman WaitzmanDepartment of Economics, University of Utah, Salt Lake City, UT.
Richard NelsonDivision of Epidemiology, Department of Internal Medicine, University of Utah, Salt Lake City, UT.
L LuAnn MinichDivision of Cardiology, Department of Pediatrics, University of Utah, Salt Lake City, UT.
Sergey KrikovDivision of Medical Genetics, Department of Pediatrics, University of Utah, Salt Lake City, UT.
Lorenzo D BottoDivision of Medical Genetics, Department of Pediatrics, University of Utah, Salt Lake City, UT.

Funding

University of Utah Center for Clinical and Translational ScienceUL1TR001067 · NCATS · UNIVERSITY OF UTAH · PI DERE, WILLARD H., HESS, RACHEL · 2013 to 2017
$19.8M
UNIVERSITY OF UTAH CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE-UL1: BPCAUL1RR025764 · NCRR · UNIVERSITY OF UTAH · PI MCCLAIN, DONALD A. · 2008 to 2011
$19.4M
University of Utah Center for Clinical and Translational Science-UL1UL1TR000105 · NCATS · UNIVERSITY OF UTAH · PI MCCLAIN, DONALD A. · 2012 to 2013
$5.1M
American Heart Association-American Stroke Association 14CRP18200023NCATS NIH HHS UL1 TR000105NCATS NIH HHS UL1 TR001067NCRR NIH HHS UL1 RR025764
6 · The paper itself

Abstract

objectiveTo assess longitudinal estimates of inpatient costs through early childhood in patients with critical congenital heart defects (CCHDs), for whom reliable estimates are scarce, using a population-based cohort of clinically validated CCHD cases. STUDY

designLongitudinal retrospective cohort of infants with CCHDs live born from 1997 to 2012 in Utah. Cases identified from birth defect registry data were linked to inpatient discharge abstracts and vital records to track inpatient days and costs through age 10 years. Costs were adjusted for inflation and discounted by 3% per year to generate present value estimates. Multivariable models identified infant and maternal factors potentially associated with higher resource utilization and were used to calculate adjusted costs by defect type.

resultsThe final statewide cohort included 1439 CCHD cases among 803 509 livebirths (1.8/1000). The average cost per affected child through age 10 years was $136 682 with a median of $74 924 because of a small number of extremely high cost children; costs were highest for pulmonary atresia with ventricular septal defect and hypoplastic left heart syndrome. Inpatient costs increased by 1.6% per year during the study period. A single birth year cohort (~50 000 births/year) had estimated expenditures of $11 902 899 through age 10 years. Extrapolating to the US population, inpatient costs for a single birth year cohort through age 10 years were ~$1 billion.

conclusionsInpatient costs for CCHDs throughout childhood are high and rising. These revised estimates will contribute to comparative effectiveness research aimed at improving the value of care on a patient and population level.

Indexed as

Health Care CostsCongenital AbnormalitiesDatabases, FactualFemaleHeart Defects, CongenitalHeart Septal Defects, VentricularHospitalizationHumansHypoplastic Left Heart SyndromeInfantInfant, NewbornInpatientsLongitudinal StudiesMaleMultivariate AnalysisNeonatal Screening

Identifiers

PMID30268400
PMCPMC11104566

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.