Trial reportBMC complementary and alternative medicine2018
The effect of Aloe Vera gel on prevention of pressure ulcers in patients hospitalized in the orthopedic wards: a randomized triple-blind clinical trial.
Trial report in BMC complementary and alternative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Herbal Medicine for the Management of Wounds: A Systematic Review of Clinical Studies.Infectious disorders drug targets · 2025Pooled it
- Dressings and topical agents for preventing pressure ulcers.The Cochrane database of systematic reviews · 2024Pooled it
- Prevalence of pressure ulcer and related factors in orthopaedic wards: A systematic review and meta-analysis.International wound journal · 2023Pooled it
- Comparison of aloe vera gel dressing with conventional dressing on pressure ulcer pain reduction: a clinical trial.BMC research notes · 2024Trial
- ChitoHeal gel use on the nasal site for prevention of N95 masks caused pressure injuries: A randomised clinical trial.International wound journal · 2023Trial
- Aloe-derived micellar emulsion dressing combination therapy for pressure ulcers: A case report and review of literature.World journal of clinical cases · 2026Article
- Antibiotic bone cement combined with vacuum sealing drainage effectively repairs sacrococcygeal pressure ulcer.American journal of translational research · 2024Article
- The Topical Formulation of Whey Protein for the Prevention of Pressure Ulcers in Critically Ill Patients: A Novel Intervention in a Randomized-Controlled Clinical Trial.Advanced biomedical research · 2023Article
- Preventive effect of cluster nursing on pressure ulcers in orthopedic patients and predictive value of serum IL-6 and TNF-α for the occurrence of pressure ulcers.American journal of translational research · 2023Article
- [Experimental Study of Using Aloe Vera Gel to Treat Diabetic Chronic Cutaneous Ulcers in Bama Miniature Pigs].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022Article
- Antibiotics-Free Compounds for Chronic Wound Healing.Pharmaceutics · 2022Review
- Comparative Evaluation of the Effect of Aloe Vera Gel, Olive Oil, and Compound Aloe Vera Gel-Olive Oil on Prevention of Pressure Ulcer: A Randomized Controlled Trial.Advanced biomedical research · 2022Article
- Efficacy of Human-Recombinant Epidermal Growth Factor Combined with Povidone-Iodine for Pressure Ulcers and Its Influence on Inflammatory Cytokines.Mediators of inflammation · 2022Article
- Pharmacological Update Properties ofMolecules (Basel, Switzerland) · 2020Review
- Iranian nurses' knowledge, attitude and behaviour on skin care, prevention and management of pressure injury: A descriptive cross-sectional study.Nursing open · 2019Article
- Review
- Modeling the Factors Associated with Nurses' Knowledge and Perceived Barriers Towards Pressure Injury Prevention: A Multi-Center Study.SAGE open nursingArticle
- Effect of Nurse-Applied Aloe Vera and Rosemary Oil Combination on Pressure Injury Prevention in Orthopaedic Surgery: A Triple-Blind Randomized Trial.SAGE open nursingArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOne of the most common orthopedic problems is the incidence of pressure ulcer followed by immobility. This study aimed to investigate the effect of Aloe Vera gel on the prevention of pressure ulcer in patients hospitalized in the orthopedic ward.
methodThis study is a randomized, triple-blind clinical trial which was done on 80 purposefully selected patients in orthopedic ward in Arak town, Iran, 2016. Patients were randomly assigned into two intervention and control groups based on blocking sampling method. In each group the routine daily cares to prevent bed sores were performed by nurses. In the intervention group in addition to routine nursing care to prevent bed sores, twice a day (hours of 9 and 21) pure Aloe Vera gel on the areas of hip, sacrum and heel were rubbed, but in the control group placebo (gel of water and starch) were used. Then sacral, hip and heel of both groups on days 3, 7 and 10 for of signs of pressure ulcers was evaluated.
resultsThe mean age of patients in the control group was (42.34 ± 12.19) and in the intervention group Was (41.71 ± 11.50) years, respectively. In the intervention group 1 patient afflicted with sore of hip and two people with sacral pressure ulcer. In the control group 3 patients affiliated with sore of hip, 8 people with sacral pressure ulcer, and 1 person had pressure sore of heel. Analysis of the data showed that both groups had statistically significant differences in the incidence of pressure ulcers (P = 0.047). This means that Aloe Vera gel could prevent the occurrence of pressure ulcers in the intervention group.
conclusionDue to the effect of Aloe Vera gel to prevent a rise in temperature, non-blanchable redness, swelling and pain of the skin of regions under study in hospitalized patients in the orthopedic ward, applying of it toward the prevention of pressure ulcers in patients at risk of pressure ulcer development is recommended.
trial registrationThis study was registered in Iranian Registry of Clinical. Trials in 07/09/2016 with the IRCT ID: IRCT2016051027825N1 .
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.