Evidence map›Paper›PMID 30268154›Full record

ArticleJournal of physiological anthropology2018

Characteristics of cardiovascular responses to an orthostatic challenge in trained spinal cord-injured individuals.

Masahiro Itoh, Masako Yamaoka Endo, Tatsuya Hojo, Miho Yoshimura, Yoshiyuki Fukuoka

Open access · goldAbstract read
In one paragraph

Article in Journal of physiological anthropology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Responses to Valsalva's maneuver in spinal cord injury do not broadly relate to vasoconstrictor capacity.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Article
  3. Article
  4. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Masahiro ItohDepartment of Physiology, Kumamoto University Graduate School of Life Sciences, 4-24-1, Kuhonji Chuou-ku, Kumamoto, 862-0976, Japan. ito@gpo.kumamoto-u.ac.jp.
Masako Yamaoka EndoDepartment of Exercise Science and Physiology, Faculty of Human Culture and Science, Prefectural University of Hiroshima, Hiroshima, Japan.
Tatsuya HojoLaboratory of Sports Medicine, Faculty of Health and Sport Science, Doshisha University, Kyoto, Japan.
Miho YoshimuraLaboratory of Sports Medicine, Faculty of Health and Sport Science, Doshisha University, Kyoto, Japan.
Yoshiyuki FukuokaLaboratory of Environmental Physiology, Faculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto, Kumamoto, Japan.
Doshisha University · JPKumamoto University · JPPrefectural University of Hiroshima · JPPrefectural University of Kumamoto · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe investigated cardiovascular responses to an orthostatic challenge in trained spinal cord-injured (SCI) individuals compared to able-bodied (AB) individuals.

methodsA total of 23 subjects participated, divided into three groups: seven were trained as spinal cord-injured (Tr-SCI) individuals, seven were able-bodied individuals trained as runners (Tr-AB), and nine were untrained able-bodied individuals (UnTr-AB). We measured the cardiovascular autonomic responses in all three groups during each 5-min head-up tilt (HUT) of 0°, 40°, and 80°. Stroke volume (SV), heart rate (HR), and cardiac output (Qc) as cardiovascular responses were measured by impedance cardiography. Changes in deoxyhemoglobin (∆[HHb]) and total hemoglobin (∆[Hb

resultsAs the HUT increased from 0° to 80°, Tr-SCI group showed less change in SV at all HUT levels even if HR increased significantly. Mean arterial pressure (MAP) also did not significantly increase as tilting increased from 0° to 80°. Regarding peripheral vascular responses, the alterations of ∆[Hb

conclusionThere is a specific mechanism whereby blood pressure is maintained during a HUT in Tr-SCI group with the elicitation of peripheral vasoconstriction and the atrophy of the vascular vessels in paraplegic lower limbs, which would be associated with less change in SV in response to an orthostatic challenge.

Indexed as

AdultCardiography, ImpedanceHemodynamicsHumansMaleMiddle AgedSpectroscopy, Near-InfraredSpinal Cord InjuriesTilt-Table TestYoung AdultCardiovascular responsesNear-infrared spectroscopyOrthostatic challengeSpinal cord injury

Identifiers

PMID30268154
PMCPMC6162881
OpenAlexW2893570604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.