Evidence map›Paper›PMID 30268114›Full record

Trial reportBMC infectious diseases2018

A crowdsourced intervention to promote hepatitis B and C testing among men who have sex with men in China: study protocol for a nationwide online randomized controlled trial.

Thomas Fitzpatrick, Kali Zhou, Yu Cheng, Po-Lin Chan, Fuqiang Cui, Weiming Tang, Katie R Mollan, Wilson Guo, Joseph D Tucker

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03482388 (A Crowdsourced Intervention to Promote Hepatitis B and C Testing Among Men Who Have Sex With Men in China), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03482388 nacompletednot on this map

A Crowdsourced Intervention to Promote Hepatitis B and C Testing Among Men Who Have Sex With Men in China: a Nationwide Online Randomized Controlled Trial

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2018 to 2018Enrolled700ConditionsHepatitis, Hepatitis B, Hepatitis CArmsCrowdsourced materials, Control
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Social innovation in diagnostics: three case studies.Infectious diseases of poverty · 2020
    Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thomas FitzpatrickSchool of Medicine, University of Washington, Seattle, WA, USA. tsfitz@uw.edu.ORCID http://orcid.org/0000-0002-0852-7291
Kali ZhouDepartment of Gastroenterology and Hepatology, University of California San Francisco, San Francisco, USA.
Yu ChengSchool of Sociology and Anthropology, Sun Yat-sen University, Guangzhou, China.
Po-Lin ChanDivision of Communicable Disease, World Health Organization Western Pacific Regional Office, Manila, Philippines.
Fuqiang CuiDepartment of Laboratorial Science and Technology, Peking University, Beijing, China.
Weiming TangUNC - Project China, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Katie R MollanSchool of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Wilson GuoGillings School of Global Public Health - Health Policy and Management, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Joseph D TuckerUNC - Project China, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Spurring Innovation in HIV Testing and Linkage: A Crowdsourcing Approach -Diversity SupplementR01AI114310 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI TUCKER, JOSEPH DAVID, WEI, CHONGYI · 2014 to 2018
$3.3M
UNC-South China STD Research Training CenterD43TW009532 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COHEN, MYRON SCOTT, TUCKER, JOSEPH DAVID · 2013 to 2017
$1.3M
Doris Duke Charitable Foundation 2016177FIC NIH HHS D43 TW009532National Institute of Allergy and Infectious Diseases 1R01AI114310-01NIAID NIH HHS P30 AI050410NIAID NIH HHS R01 AI114310UNC CFAR P30 AI50410World Health Organization 001
6 · The paper itself

Abstract

backgroundThe World Health Organization recommends all men who have sex with men (MSM) receive Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) testing. MSM in China are a high-risk group for HBV and HCV infection, but test uptake is low. Crowdsourcing invites a large group to solve a problem and then shares the solution with the public. This nationwide online randomized controlled trial will evaluate the effectiveness of a crowdsourced intervention to increase HBV and HCV testing among MSM in China.

methodsSeven hundred MSM will be recruited through social media operated by MSM organizations in China. Eligible participants will be born biologically male, age 16 years or older, report previous anal sex with another man, and reside in China. After completing a baseline online survey, participants will be randomly assigned to intervention or control arms with a 1:1 allocation ratio. The intervention will include two components: (1) a multimedia component will deliver two videos and two images promoting HBV and HCV testing developed through a crowdsourcing contest in China; (2) a participatory component will invite men to submit suggestions for how to improve crowdsourced videos and images. The control arm will not view any images or videos and will not be invited to submit suggestions. All participants will be offered reimbursement for HBV and HCV testing costs. The primary outcome is HBV and HCV test uptake confirmed through electronic submission of test report photos within four weeks of enrolment. Secondary outcomes include self-reported HBV and HCV test uptake, HBV vaccination uptake, and change in stigma toward people living with HBV after four weeks. Primary and secondary outcomes will be calculated using intention to treat and as-exposed analyses and compared using two-sided 95% confidence intervals. DISCUSSION: Few previous studies have evaluated interventions to increase HBV and HCV testing in middle-income countries with a high burden of hepatitis. Delivering a crowdsourced intervention using social media is a novel approach to increasing hepatitis testing rates. HBV and HCV test uptake will be confirmed through test report photos, avoiding the limitations of self-reported testing outcomes.

trial registrationNCT03482388 (29 March 2018).

Indexed as

AdolescentAdultChinaCrowdsourcingHepatitis BHepatitis B Surface AntigensHepatitis B VaccinesHepatitis CHepatitis C AntibodiesHIV InfectionsHomosexuality, MaleHumansMaleSelf ReportVaccinationYoung AdultHepatitis B Surface AntigensHepatitis B VaccinesHepatitis C AntibodiesChinaCrowdsourcingHepatitis B virus (HBV)Hepatitis C virus (HCV)Men who have sex with men (MSM)Testing

Identifiers

PMID30268114
PMCPMC6162889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.