Evidence map›Paper›PMID 30267716›Full record

ArticleMicrovascular research2019

Evaluating changes of blood flow in retina, choroid, and outer choroid in rats in response to elevated intraocular pressure by 1300 nm swept-source OCT.

Jingjiang Xu, Yuandong Li, Shaozhen Song, William Cepurna, John Morrison, Ruikang K Wang

Abstract read
In one paragraph

Article in Microvascular research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jingjiang XuUniversity of Washington, Department of Bioengineering, Seattle, WA 98195, USA.
Yuandong LiUniversity of Washington, Department of Bioengineering, Seattle, WA 98195, USA.
Shaozhen SongUniversity of Washington, Department of Bioengineering, Seattle, WA 98195, USA.
William CepurnaCasey Eye Institute, Oregon Health & Science University, Portland, OR 97239, USA.
John MorrisonCasey Eye Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Ruikang K WangUniversity of Washington, Department of Bioengineering, Seattle, WA 98195, USA; University of Washington, Department of Ophthalmology, Seattle, WA 98104, USA. Electronic address: wangrk@uw.edu.
University of Washington · USOregon Health & Science University · US

Funding

Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TED S ACOTT · 1995 to 2026
$19.4M
STUDIES IN GLAUCOMATOUS OPTIC NERVE DAMAGER01EY010145 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MORRISON, JOHN C · 1993 to 2023
$8.9M
OPTICAL MICROANGIOGRAHY OF CEREBROVASCULAR PERFUSIONR01HL093140 · NHLBI · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2008 to 2017
$4.2M
Ultra-wide field optical coherence tomography based angiography for imaging diabetic retinopathyR01EY028753 · NEI · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2018 to 2021
$2.2M
NON-INVASIVE REAL-TIME LABEL-FREE 3D IMAGING OF RETINAL MICROCIRCULATIONR01EY024158 · NEI · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2014 to 2017
$1.7M
NEI NIH HHS P30 EY010572NEI NIH HHS R01 EY010145NEI NIH HHS R01 EY024158NEI NIH HHS R01 EY028753NHLBI NIH HHS R01 HL093140
6 · The paper itself

Abstract

We report the development of a 1300 nm swept-source optical coherence tomography (SS-OCT) system specifically designed to perform OCT imaging and optical microangiography (OMAG) in rat eyes in vivo and its use in evaluating the effects of intraocular pressure (IOP) elevation on ocular circulation. The swept laser is operated in single longitude mode with a 90 nm bandwidth centered at 1300 nm and 200 kHz A-line rate, providing remarkable sensitivity fall-off performance along the imaging depth, a larger field of view of 2.5 × 2.5 mm

Indexed as

Intraocular PressureMicrocirculationAnimalsBlood Flow VelocityChoroidDiagnostic Techniques, OphthalmologicalDisease Models, AnimalEquipment DesignOcular HypertensionPerfusion ImagingPredictive Value of TestsRats, Inbred BNRegional Blood FlowRetinal VesselsTime FactorsTomography, Optical CoherenceCircle of Zinn-HallerGlaucomaIntraocular pressureOcular perfusionOptical coherence tomographyOptical microangiographyOptic nerve headSwept source OCT

Identifiers

PMID30267716
PMCPMC6286199
OpenAlexW2892405076

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.