Evidence map›Paper›PMID 30267538›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2019

Quantifying bias between reported last menstrual period and ultrasonography estimates of gestational age in Lusaka, Zambia.

Joan T Price, Jennifer Winston, Bellington Vwalika, Stephen R Cole, Marie C D Stoner, Mwansa K Lubeya, Andrew Kumwenda, Jeffrey S A Stringer

Abstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Observational
  5. Deep learning to estimate gestational age from fly-to cineloop videos: A novel approach to ultrasound quality control.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2024
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  14. Observational
  15. Methodological Considerations for Preterm Birth Research.Frontiers in global women's health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Joan T PriceDepartment of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jennifer WinstonDepartment of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Bellington VwalikaWomen and Newborn Hospital, University Teaching Hospital, Lusaka, Zambia.
Stephen R ColeDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Marie C D StonerDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Mwansa K LubeyaWomen and Newborn Hospital, University Teaching Hospital, Lusaka, Zambia.
Andrew KumwendaWomen and Newborn Hospital, University Teaching Hospital, Lusaka, Zambia.
Jeffrey S A StringerDepartment of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · USUniversity Teaching Hospital · ZMUniversity of Zambia · ZM

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
UNC Global Women’s Health FellowshipT32HD075731 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2013 to 2024
$2.4M
The UNC-UNZA-Wits Partnership for HIV and Women's Reproductive HealthD43TW010558 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H., CHIBWESHA, CARLA J · 2017 to 2021
$1.5M
A Career Development Award in HIV-Associated Preterm Birth and its PreventionK01TW010857 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PRICE, JOAN · 2017 to 2021
$682k
Center for AIDS ResearchFIC NIH HHS D43 TW010558FIC NIH HHS K01 TW010857Global Alliance to Prevent Prematurity and StillbirthNational Institutes of HealthNIAID NIH HHS P30 AI050410NICHD NIH HHS P2C HD050924NICHD NIH HHS T32 HD075731
6 · The paper itself

Abstract

objectiveTo quantify differences in assessing preterm delivery when calculating gestational age from last menstrual period (LMP) versus ultrasonography biometry.

methodsThe Zambian Preterm Birth Prevention Study is an ongoing prospective cohort study that commenced enrolment in August 2015 at Women and Newborn Hospital of University Teaching Hospital in Lusaka, Zambia. Women at less than 20 weeks of pregnancy who were enrolled between August 17, 2015, and August 31, 2017, and underwent ultrasonography examination were included in the present analysis. The primary outcome was the difference between ultrasonography- and LMP-based estimated gestational age. Associations between baseline predictors and outcomes were assessed using simple regression. The proportion of preterm deliveries using LMP- and ultrasonography-derived gestational dating was calculated using Kaplan-Meier analysis.

resultsThe analysis included 942 women. The discrepancy between estimating gestational age using ultrasonography and LMP increased with greater gestational age at presentation and among patients with no history of preterm delivery. In a Kaplan-Meier analysis of 692 deliveries, 140 (20.2%, 95% confidence interval [CI] 17.7-23.0) and 79 (11.4%, 95% CI 9.6-13.6) deliveries were classified as preterm by LMP and ultrasonography estimates, respectively.

conclusionTaking ultrasonography as a standard, a bias was observed in LMP-based gestational age estimates, which increased with advancing gestation at presentation. This resulted in misclassification of term deliveries as preterm.

Indexed as

Gestational AgeMenstrual CycleAdultFemaleHumansInfant, NewbornObserver VariationPregnancyPremature BirthProspective StudiesUltrasonography, PrenatalYoung AdultZambiaGestational ageGestational age estimationLast menstrual periodPreterm birthUltrasonographyZambia

Identifiers

PMID30267538
PMCPMC6283668
OpenAlexW2893237588

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.