Evidence map›Paper›PMID 30267357›Full record

Trial reportClinical rheumatology2019

Glucocorticoid injections for greater trochanteric pain syndrome: a randomised double-blind placebo-controlled (GLUTEAL) trial.

Michael John Nissen, Laure Brulhart, Antonio Faundez, Axel Finckh, Delphine Sophie Courvoisier, Stéphane Genevay

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Clinical rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Article
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  13. Article
  14. Elusive trochanteric bursitis relief.Clinical rheumatology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Michael John NissenDepartment of Rheumatology, Geneva University Hospital, 26 Avenue Beau-Séjour, 1211, Geneva 14, Switzerland. michael.j.nissen@hcuge.ch.ORCID http://orcid.org/0000-0002-6326-1764
Laure BrulhartDepartment of Rheumatology, Neuchâtel Hospital, Neuchâtel, Switzerland.
Antonio FaundezDepartment of Orthopaedics, Geneva University Hospital, Geneva, Switzerland.
Axel FinckhDepartment of Rheumatology, Geneva University Hospital, 26 Avenue Beau-Séjour, 1211, Geneva 14, Switzerland.
Delphine Sophie CourvoisierDepartment of Rheumatology, Geneva University Hospital, 26 Avenue Beau-Séjour, 1211, Geneva 14, Switzerland.
Stéphane GenevayDepartment of Rheumatology, Geneva University Hospital, 26 Avenue Beau-Séjour, 1211, Geneva 14, Switzerland.
Hôpital Beau-Séjour · CHHospital Neuchâtel · CHUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small observational studies suggest that local glucocorticoid (GC) injection may be effective in the management of the greater trochanteric pain syndrome (GTPS). The objective was to perform the first randomised double-blind placebo-controlled trial to investigate the efficacy of local GC injection in the management of GTPS. The trial was conducted between November 2011 and May 2015. Inclusion criteria included lateral hip pain (LHP) for greater than 1 month, a LHP score of ≥ 4/10 and typical LHP reproduced by palpation of the greater trochanter. Participants were randomised in a 1:1 ratio to injection with a combination of local anaesthetic and GC (intervention) or injection with normal saline solution (placebo). The primary outcome of interest was the difference in pain intensity at 4 weeks post-injection between the two groups. Patients were followed for 6 months. A total of 46 patients were included. There were no significant differences between the two groups in terms of pain reduction at 1 month (p = 0.23). When including all measures in the first 4 weeks and using multilevel regression, there was a trend towards improvement in pain scores in favour of the intervention group (p = 0.08). There were no significant differences in pain scores between groups at 3 and 6 months. In the management of GTPS, local glucocorticoid injections are of no greater efficacy than injection of normal saline solution. Given the lack of long-term improvement and the potential for cortisone-related side effects, this intervention is of limited benefit.

Indexed as

FemurHipAdultAgedAnesthetics, LocalBetamethasoneChronic PainDouble-Blind MethodFemaleGlucocorticoidsHumansInjectionsLidocaineMaleMiddle AgedAnesthetics, LocalBetamethasoneGlucocorticoidsLidocaineGlucocorticoidsHip jointInjectionsPainTendinopathy

Identifiers

PMID30267357
OpenAlexW2892975728

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.