Trial reportClinical oral investigations2019
Randomized in situ study on the efficacy of CO
Trial report in Clinical oral investigations, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Clinical and ex-vivo effect of LASERs on prevention of early-enamel caries: systematic review & meta-analyses.Lasers in medical science · 2024Pooled it
- Controlled heating between 100 and 500 degrees celsius improves enamel resistance to erosion in vitro.Scientific reports · 2026Article
- Effect of Combined CO₂ Laser Irradiation and Sodium Fluoride Varnish on Enamel Surface Morphology and Surface Elemental Composition: An In Vitro Split-Tooth Study.F1000Research · 2026Article
- Effect of Laser Irradiation on Fluoride Uptake in Primary Teeth Treated with 38% Silver Diamine Fluoride or 5% Sodium Fluoride Varnish: AnInternational journal of clinical pediatric dentistry · 2025Article
- Randomized in situ evaluation of surface polishing protocols on the caries-protective effect of resin Infiltrant.Scientific reports · 2022Article
- The effect of COLasers in medical science · 2020Article
- The Effect of Er:YAG Laser Irradiation Combined With Fluoride Application on the Resistance of Primary and Permanent Dental Enamel to Erosion.Journal of lasers in medical sciences · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
Abstract
objectivesThe aim of this double-blind, randomized in situ study was to evaluate the erosion-preventive effect of a specific set of CO
methodsTwo hundred forty bovine enamel blocks were prepared for individual palatal appliances (n = 6 samples/appliance). The study had four phases of 5 days each, with ten volunteers and the following treatments: CO
resultsAt all analyzing days, both laser groups caused the lowest means of enamel loss, which were also statistically significant lower than C (p < 0.05). At day 5, FL means ± SD (33.6 ± 12.6 μm) were even significantly lower than all other groups (C 67.8 ± 15.4 μm; F 57.5 ± 20.3 μm; L 46.8 ± 14.5 μm). Significantly increased enamel fluoride uptake was observed for both fluoride-containing groups (p < 0.05) at day 1.
conclusionCompared to the control, the CO CLINICAL RELEVANCE: Combined CO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.