Evidence map›Paper›PMID 30267268›Full record

ArticleNeurotoxicity research2019

Antidepressant-Like Activity of Typical Antidepressant Drugs in the Forced Swim Test and Tail Suspension Test in Mice Is Augmented by DMPX, an Adenosine A

Ewa Poleszak, Aleksandra Szopa, Karolina Bogatko, Elżbieta Wyska, Sylwia Wośko, Katarzyna Świąder, Urszula Doboszewska, Aleksandra Wlaź, Andrzej Wróbel, Piotr Wlaź and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Neurotoxicity research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Antidepressant Effect and Mechanism ofJournal of microbiology and biotechnology · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Influence ofLife (Basel, Switzerland) · 2021
    Article
  17. Article
  18. Biological Evaluation ofACS omega · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ewa PoleszakDepartment of Applied Pharmacy, Medical University of Lublin, Chodźki 1, PL 20-093, Lublin, Poland. ewa.poleszak@umlub.pl.
Aleksandra SzopaDepartment of Applied Pharmacy, Medical University of Lublin, Chodźki 1, PL 20-093, Lublin, Poland. aleksandra.szopa@umlub.pl.ORCID http://orcid.org/0000-0002-7756-2904
Karolina BogatkoDepartment of Applied Pharmacy, Medical University of Lublin, Chodźki 1, PL 20-093, Lublin, Poland.
Elżbieta WyskaDepartment of Pharmacokinetics and Physical Pharmacy, Collegium Medicum, Jagiellonian University, Medyczna 9, PL 30-688, Kraków, Poland.
Sylwia WośkoDepartment of Applied Pharmacy, Medical University of Lublin, Chodźki 1, PL 20-093, Lublin, Poland.
Katarzyna ŚwiąderDepartment of Applied Pharmacy, Medical University of Lublin, Chodźki 1, PL 20-093, Lublin, Poland.
Urszula DoboszewskaDepartment of Animal Physiology, Institute of Biology and Biochemistry, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka 19, PL 20-033, Lublin, Poland.
Aleksandra WlaźDepartment of Pathophysiology, Medical University of Lublin, Jaczewskiego 8, PL 20-090, Lublin, Poland.
Andrzej WróbelSecond Department of Gynecology, Medical University of Lublin, Jaczewskiego 8, PL 20-090, Lublin, Poland.
Piotr WlaźDepartment of Animal Physiology, Institute of Biology and Biochemistry, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka 19, PL 20-033, Lublin, Poland.
Anna SerefkoDepartment of Applied Pharmacy, Medical University of Lublin, Chodźki 1, PL 20-093, Lublin, Poland.
Medical University of Lublin · PLMaria Curie-Skłodowska University · PLJagiellonian University · PL

Funding

Uniwersytet Medyczny w Lublinie DS 48
6 · The paper itself

Abstract

Unsatisfactory therapeutic effects of currently used antidepressants force to search for new pharmacological treatment strategies. Recent research points to the relationship between depressive disorders and the adenosinergic system. Therefore, the main goal of our studies was to evaluate the effects of DMPX (3 mg/kg, i.p.), which possesses selectivity for adenosine A

Indexed as

Adenosine A2 Receptor AntagonistsAnimalsAntidepressive AgentsDepressionDose-Response Relationship, DrugDrug SynergismHindlimb SuspensionLocomotionMaleMiceReceptor, Adenosine A2ASwimmingTheobromine3,7-dimethyl-1-propargylxanthineAdenosine A2 Receptor AntagonistsAntidepressive AgentsReceptor, Adenosine A2ATheobromineAntidepressantsDMPXForced swim testMiceTail suspension test

Identifiers

PMID30267268
PMCPMC6331646
OpenAlexW2893774910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.