Evidence map›Paper›PMID 30267208›Full record

ArticleActa neurochirurgica2018

Optimal cerebral perfusion pressure via transcranial Doppler in TBI: application of robotic technology.

Frederick A Zeiler, Marek Czosnyka, Peter Smielewski

Abstract read
In one paragraph

Article in Acta neurochirurgica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Individualized autoregulation-guided arterial blood pressure management in neurocritical care.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. The pressure reactivity index as a measure of cerebral autoregulation and its application in traumatic brain injury management.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2023
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Frederick A ZeilerDivision of Anaesthesia, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK. umzeiler@myumanitoba.ca.ORCID 0000-0003-1737-0510
Marek CzosnykaDivision of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital, University of Cambridge, Cambridge, CB2 0QQ, UK.
Peter SmielewskiDivision of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital, University of Cambridge, Cambridge, CB2 0QQ, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Individualized cerebral perfusion pressure (CPP) targets may be derived via assessing the minimum of the parabolic relationship between an index of cerebrovascular reactivity and CPP. This minimum is termed the optimal CPP (CPPopt), and literature suggests that the further away CPP is from CPPopt, the worse is clinical outcome in adult traumatic brain injury (TBI). Typically, CPPopt estimation is based on intracranial pressure (ICP)-derived cerebrovascular reactivity indices, given ICP is commonly measured and provides continuous long duration data streams. The goal of this study is to describe for the first time the application of robotic transcranial Doppler (TCD) and the feasibility of determining CPPopt based on TCD autoregulation indices.

Indexed as

Cerebrovascular CirculationBrain Injuries, TraumaticHumansRoboticsUltrasonography, DopplerCPP optimumRobotic transcranial DopplerTBITCDTraumatic brain injury

Identifiers

PMID30267208
PMCPMC6209007

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.