ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2018
Left atrial appendage exclusion during mitral valve surgery and stroke in atrial fibrillation.
Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Position paper of the Polish Society of Cardiothoracic Surgeons and the Heart Rhythm Association of the Polish Society of Cardiology on atrial fibrillation hybrid management.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2025Article
- Surgical Methods and Devices for Atrial Fibrillation.Reviews in cardiovascular medicine · 2025Review
- Systematic review and meta-analysis of left atrial appendage closure's influence on early and long-term mortality and stroke.JTCVS open · 2024Article
- Arrhythmias in Patients With Valvular Heart Disease: Gaps in Knowledge and the Way Forward.Frontiers in cardiovascular medicine · 2022Review
- Understanding the molecular role of syndecan-1 in the regulation of caspase-6 during the progression of cardiac arrhythmia.Experimental and therapeutic medicine · 2021Article
- Percutaneous Left Atrial Appendage Occlusion: An Emerging Option in Patients with Atrial Fibrillation at High Risk of Bleeding.Medicina (Kaunas, Lithuania) · 2021Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to determine whether surgical left atrial appendage (LAA) exclusion performed during mitral valve surgery is associated with a reduction in cerebrovascular events in patients with atrial fibrillation.
methodsWe retrospectively studied patients with atrial fibrillation who underwent mitral valve surgery from 1/1/2001 through 12/31/2014. We screened 1352 patients using ICD-9 codes and included 281 patients in the study. The primary end point was a composite of strokes and transient ischemic attacks occurring within 5 years after surgery. Secondary end points were stroke, transient ischemic attack, and all-cause mortality.
resultsThe LAA exclusion group (n = 188) had a lower prevalence of female gender, hypertension, and diabetes mellitus compared with the non-LAA exclusion group (n = 93). The CHA
conclusionsLAA exclusion was associated with fewer cerebrovascular events. However, this benefit was seen only with concomitant surgical ablation.
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Registered trials
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