Evidence map›Paper›PMID 30266881›Full record

ArticleThorax2019

Emerging biology of persistent mucous cell hyperplasia in COPD.

Renat Shaykhiev

Open access · bronzeAbstract readEditorialComment
In one paragraph

Article in Thorax, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. IFN-Mediated Bronchial Epithelium Cellular Senescence in Chronic Obstructive Pulmonary Disease.American journal of respiratory cell and molecular biology · 2025
    Article
  3. A translational view of airway epithelial dysfunction in COPD.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  4. Review
  5. Article
  6. High-throughput Mucus Microrheology for Phenotyping and Disease Modeling.bioRxiv : the preprint server for biology · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Animal models and mechanisms of tobacco smoke-induced chronic obstructive pulmonary disease (COPD).Journal of toxicology and environmental health. Part B, Critical reviews · 2023
    Review
  13. Article
  14. Review
  15. Increased Expression ofFrontiers in immunology · 2022
    Article
  16. LKB1 deficiency upregulates RELM-α to drive airway goblet cell metaplasia.Cellular and molecular life sciences : CMLS · 2021
    Article
  17. Article
  18. Review
  19. Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD.bioRxiv : the preprint server for biology · 2020
    Article
  20. A 'tad' of hope in the fight against airway disease.Biochemical Society transactions · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Cornell University · US

Funding

Defective FGFR2 Signaling in the Small Airway Basal Progenitor Cells in COPDR01HL123544 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SHAYKHIEV, RENAT · 2015 to 2019
$2.1M
Amphiregulin-driven COPD-relevant Remodeling of Human Airway EpitheliumR01HL127393 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SHAYKHIEV, RENAT · 2016 to 2019
$1.7M
NHLBI NIH HHS R01 HL123544NHLBI NIH HHS R01 HL127393
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Pulmonary Disease, Chronic ObstructiveRhinovirusEpithelial CellsGoblet CellsHumansHyperplasiaReceptor, Notch3NOTCH3 protein, humanReceptor, Notch3airway epitheliumcopd ÀÜ mechanismscopd exacerbationscopd pathologyviral infection

Identifiers

PMID30266881
PMCPMC6347109
OpenAlexW2893202696

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.