Evidence map›Paper›PMID 30266833›Full record

ArticleJournal of lipid research2018

Use of plasma metabolomics to analyze phenotype-genotype relationships in young hypercholesterolemic females.

Xiang Zhang, Antoine Rimbert, Willem Balder, Aeilko Having Zwinderman, Jan Albert Kuivenhoven, Geesje Margaretha Dallinga-Thie, Albert Kornelis Groen

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of lipid research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiang ZhangDepartments of Experimental Vascular Medicine University of Amsterdam, Amsterdam, The Netherlands.
Antoine RimbertDepartment of Pediatrics, Section Molecular Genetics, University of Groningen, Groningen, The Netherlands.
Willem BalderDepartment of Pediatrics, Section Molecular Genetics, University of Groningen, Groningen, The Netherlands.
Aeilko Having ZwindermanClinical Epidemiology, Biostatistics, and Bioinformatics, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Jan Albert KuivenhovenDepartment of Pediatrics, Section Molecular Genetics, University of Groningen, Groningen, The Netherlands.
Geesje Margaretha Dallinga-ThieDepartments of Experimental Vascular Medicine University of Amsterdam, Amsterdam, The Netherlands.
Albert Kornelis GroenDepartments of Experimental Vascular Medicine University of Amsterdam, Amsterdam, The Netherlands a.k.groen@amc.uva.nl.
University of Amsterdam · NLUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypercholesterolemia is characterized by high plasma LDL cholesterol and often caused by genetic mutations in LDL receptor (

Indexed as

AdultFemaleGenotypeHigh-Throughput Nucleotide SequencingHumansHyperlipoproteinemia Type IIMetabolomicsPhenotypePrincipal Component Analysisgeneticshypercholesterolemialow density lipoproteinmetabolomicstriglyceride

Identifiers

PMID30266833
PMCPMC6210900
OpenAlexW2893221259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.