ArticleProceedings of the National Academy of Sciences of the United States of America2018
Neutral and selective dynamics in a synthetic microbial community.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- In anaerobic reactors the microbial community structure depends on feed type, with no "keystone" species tied to COD removal.Frontiers in microbiology · 2025Article
- A systematic discussion and comparison of the construction methods of synthetic microbial community.Synthetic and systems biotechnology · 2024Review
- The evolution of autonomy from two cooperative specialists in fluctuating environments.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Long-distance movement dynamics shape host microbiome richness and turnover.FEMS microbiology ecology · 2024Article
- Niche differentiation in microbial communities with stable genomic traits over time in engineered systems.The ISME journal · 2024Article
- Effects of plant tissue permeability on invasion and population bottlenecks of a phytopathogen.Nature communications · 2024Article
- What are patterns of rise and decline?Royal Society open science · 2023Review
- Promotion of plasmid maintenance by heterogeneous partitioning of microbial communities.Cell systems · 2023Article
- Quantifying drift-selection balance using an agent-based biofilm model of identical heterotrophs under low-nutrient conditions.Interface focus · 2023Article
- Synthetic Denitrifying Communities Reveal a Positive and Dynamic Biodiversity-Ecosystem Functioning Relationship during Experimental Evolution.Microbiology spectrum · 2023Article
- Best Practices in Designing, Sequencing, and Identifying Random DNA Barcodes.Journal of molecular evolution · 2023Review
- A Reproducible and Tunable Synthetic Soil Microbial Community Provides New Insights into Microbial Ecology.mSystems · 2022Article
- Guided by the principles of microbiome engineering: Accomplishments and perspectives for environmental use.mLife · 2022Review
- Article
- Quantifying rapid bacterial evolution and transmission within the mouse intestine.Cell host & microbe · 2021Article
- Predicting plasmid persistence in microbial communities by coarse-grained modeling.BioEssays : news and reviews in molecular, cellular and developmental biology · 2021Article
- Synergistically promoting plant health by harnessing synthetic microbial communities and prebiotics.iScience · 2021Review
- Towards an engineering theory of evolution.Nature communications · 2021Review
- Experimental Evolution in Plant-Microbe Systems: A Tool for Deciphering the Functioning and Evolution of Plant-Associated Microbial Communities.Frontiers in microbiology · 2021Review
- Metagenomics for taxonomy profiling: tools and approaches.Bioengineered · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ecologists debate the relative importance of selective vs. neutral processes in understanding biodiversity. This debate is especially pertinent to microbial communities, which play crucial roles in areas such as health, disease, industry, and the environment. Here, we created a synthetic microbial community using heritable genetic barcodes and tracked community composition over repeated rounds of subculture with immigration. Consistent with theory, we find a transition exists between neutral and selective regimes, and the crossover point depends on the fraction of immigrants and the magnitude of fitness differences. Neutral models predict an increase in diversity with increased carrying capacity, while our selective model predicts a decrease in diversity. The community here lost diversity with an increase in carrying capacity, highlighting that using the correct model is essential for predicting community response to change. Together, these results emphasize the importance of including selection to obtain realistic models of even simple systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.