Evidence map›Paper›PMID 30266729›Full record

Trial reportApplied and environmental microbiology2018

Metagenomic Insights into the Degradation of Resistant Starch by Human Gut Microbiota.

Marius Vital, Adina Howe, Nathalie Bergeron, Ronald M Krauss, Janet K Jansson, James M Tiedje

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Applied and environmental microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Frontiers in microbiology · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Marius VitalCenter for Microbial Ecology, Michigan State University, East Lansing, Michigan, USA.
Adina HoweDepartment of Agricultural and Biosystems Engineering, Iowa State University, Ames, Iowa, USA.
Nathalie BergeronChildren's Hospital Oakland Research Institute, Oakland, California, USA.
Ronald M KraussChildren's Hospital Oakland Research Institute, Oakland, California, USA.
Janet K JanssonPacific Northwest National Laboratory, Biological Sciences Division, Richland, Washington, USA.
James M TiedjeCenter for Microbial Ecology, Michigan State University, East Lansing, Michigan, USA tiedjej@msu.edu.
Helmholtz Centre for Infection Research · DEIowa State University · USMichigan State University · USPacific Northwest National Laboratory · US

Funding

Engaging University of California Stakeholders for Biorespository ResearchUL1TR000004 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$78.0M
The Role of the Gut Microbiota in Ulcerative ColitisUH3DK083993 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHANG, EUGENE B, MEYER, FOLKER · 2010 to 2012
$8.2M
Effects of resistant starch on lipid and glucose metabolism in insulin resistanceRC1DK086472 · NIDDK · CHILDREN'S HOSPITAL & RES CTR AT OAKLAND · PI BERGERON, NATHALIE, KRAUSS, RONALD M · 2009 to 2010
$1000k
NCATS NIH HHS UL1 TR000004NIDDK NIH HHS RC1 DK086472NIDDK NIH HHS UH3 DK083993
6 · The paper itself

Abstract

Several studies monitoring alterations in the community structure upon resistant starch (RS) interventions are available, although comprehensive function-based analyses are lacking. Recently, a multiomics approach based on 16S rRNA gene sequencing, metaproteomics, and metabolomics on fecal samples from individuals subjected to high and low doses of type 2 RS (RS2; 48 g and 3 g/2,500 kcal, respectively, daily for 2 weeks) in a crossover intervention experiment was performed. In the present study, we did pathway-based metagenomic analyses on samples from a subset of individuals (

Indexed as

Gastrointestinal MicrobiomeAdolescentBacteriaDiabetes Mellitus, Type 2FecesFemaleHumansMaleMetagenomicsPhylogenyStarchStarchbutyratedietgut microbiotametagenomicsresistant starchshort-chain fatty acids

Identifiers

PMID30266729
PMCPMC6238065
OpenAlexW2894081250

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.