ArticleLangmuir : the ACS journal of surfaces and colloids2019
Ultralow Fouling and Functionalizable Surface Chemistry Based on Zwitterionic Carboxybetaine Random Copolymers.
Article in Langmuir : the ACS journal of surfaces and colloids, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- A tough semi-dry hydrogel electrode with anti-bacterial properties for long-term repeatable non-invasive EEG acquisition.Microsystems & nanoengineering · 2025Article
- Development of Functional Biointerface Using Mixed Zwitterionic Silatranes.Langmuir : the ACS journal of surfaces and colloids · 2024Article
- Enzymatically Built Nanoenabled Antimicrobial Coating on Urinary Catheters.ACS applied materials & interfaces · 2024Article
- Bioinspired Dopamine andPolymers · 2024Article
- Unravelling Surface Modification Strategies for Preventing Medical Device-Induced Thrombosis.Advanced healthcare materials · 2024Review
- Article
- Caffeine and Cationic Copolymers with Antimicrobial Properties.ACS bio & med chem Au · 2023Article
- Bio-inspired hemocompatible surface modifications for biomedical applications.Progress in materials science · 2022Article
- Zwitterionic Polypeptoids: A Promising Class of Antifouling Bioinspired Materials.Materials (Basel, Switzerland) · 2022Article
- Polycarboxybetaine-Based Hydrogels for the Capture and Release of Circulating Tumor Cells.Gels (Basel, Switzerland) · 2022Article
- Application of Hexanoyl Glycol Chitosan as a Non-cell Adhesive Polymer in Three-Dimensional Cell Culture.ACS omega · 2022Article
- Molecular Dynamics Study on Properties of Hydration Layers above Polymer Antifouling Membranes.Molecules (Basel, Switzerland) · 2022Article
- Fabrication of Polysulfobetaine Gradient Coating via Oxidation Polymerization of Pyrogallol To Modulate Biointerfaces.ACS omega · 2022Article
- Polyelectrolytes as Building Blocks for Next-Generation Membranes with Advanced Functionalities.ACS applied polymer materials · 2021Review
- Integrating Emerging Polymer Chemistries for the Advancement of Recyclable, Biodegradable, and Biocompatible Electronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Conjugation of Polysulfobetaine via Poly(pyrogallol) Coatings for Improving the Antifouling Efficacy of Biomaterials.ACS omega · 2021Article
- Zwitterionic liquid crystalline polythiophene as an antibiofouling biomaterial.Journal of materials chemistry. B · 2021Article
- PLL-Poly(HPMA) Bottlebrush-Based Antifouling Coatings: Three Grafting Routes.Langmuir : the ACS journal of surfaces and colloids · 2020Article
- Functionalizable Antifouling Coatings as Tunable Platforms for the Stress-Driven Manipulation of Living Cell Machinery.Biomolecules · 2020Article
- Zwitterionic Porous Conjugated Polymers as a Versatile Platform for Antibiofouling Implantable Bioelectronics.ACS applied polymer materials · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Here, we report a simple yet effective surface-modification approach to imparting hydrophobic surfaces with superhydrophilicity using ultralow fouling/functionalizable carboxybetaine (CB) copolymers via a dip-coating technique. A new series of CB random copolymers with varying amphiphilicities were synthesized and coated on hydrophobic polypropylene (PP) and polystyrene (PS) surfaces. The nonfouling capability of each coating was screened by an enzyme-linked immunosorbent assay (ELISA) and further comprehensively assessed against 100% human serum by a Micro BCA protein assay kit. The random copolymer containing ∼30 mol % CB units showed superhydrophilicity with the highest air contact angle of more than 165° in DI water and the best nonfouling capability against 100% human blood serum. Surfaces of a 96-well plate coated with the optimal CB random copolymer had a significantly better nonfouling capability than those of a commercial 96-well plate with an ultralow attachment surface. The adhesion of mouse embryonic fibroblast cells (NIH3T3) was completely inhibited on surfaces coated with CB random copolymers. Furthermore, the optimal nonfouling CB copolymer surface was functionalized with an antigen via covalent bonding where its specific interactions with its antibody were verified. Thus, this CB random copolymer is capable of imparting both ultralow fouling and functionalizable capabilities to hydrophobic surfaces for blood-contacting devices.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.