Evidence map›Paper›PMID 30264896›Full record

Trial reportMovement disorders : official journal of the Movement Disorder Society2018

Speech treatment in Parkinson's disease: Randomized controlled trial (RCT).

Lorraine Ramig, Angela Halpern, Jennifer Spielman, Cynthia Fox, Katherine Freeman

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Movement disorders : official journal of the Movement Disorder Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  12. Review
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  14. Voice and Speech in Atypical Parkinsonian Disorders.Movement disorders clinical practice · 2026
    Review
  15. Aerodynamic and Acoustic Characteristics of Nasal Airflow in Parkinson's Disease.Journal of speech, language, and hearing research : JSLHR · 2026
    Article
  16. Review
  17. Practice Parameters That Influence Vocal Motor Adaptation in Altered Auditory Feedback Paradigms.Journal of speech, language, and hearing research : JSLHR · 2026
    Article
  18. Sensorimotor Adaptation to a Nonuniform Formant Perturbation Is Preserved in Healthy Aging.Journal of speech, language, and hearing research : JSLHR · 2026
    Article
  19. Article
  20. Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lorraine RamigUniversity of Colorado-Boulder, Boulder, Colorado, USA.
Angela HalpernUniversity of Colorado-Boulder, Boulder, Colorado, USA.
Jennifer SpielmanUniversity of Colorado-Boulder, Boulder, Colorado, USA.
Cynthia FoxNational Center for Voice and Speech-Denver, Denver, Colorado, USA.
Katherine FreemanFlorida Atlantic University-Boca Raton, Boca Raton, Florida, USA.

Funding

EFFICACY OF VOICE TREATMENT FOR PARKINSONS DISEASER01DC001150 · NIDCD · UNIVERSITY OF COLORADO AT BOULDER · PI RAMIG, LORRAINE O. · 1990 to 2011
$5.8M
LSVT Global, Inc.LSVT Global, Inc., Tucson, ArizonaNational Institutes of Health-National Institute of Deafness and Other Communication Disorders R01 DC01150National Institutes of Health-National Institute of Deafness and Other Communication Disorders (NIH-NIDCD) R01 DC01150NIDCD NIH HHS R01 DC001150
6 · The paper itself

Abstract

backgroundAs many as 89% of people with Parkinson's disease (PD) develop speech disorders.

objectivesThis randomized controlled trial evaluated two speech treatments for PD matched in intensive dosage and high-effort mode of delivery, differing in subsystem target: voice (respiratory-laryngeal) versus articulation (orofacial-articulatory).

methodsPD participants were randomized to 1-month LSVT LOUD (voice), LSVT ARTIC (articulation), or UNTXPD (untreated) groups. Speech clinicians specializing in PD delivered treatment. Primary outcome was sound pressure level (SPL) in reading and spontaneous speech, and secondary outcome was participant-reported Modified Communication Effectiveness Index (CETI-M), evaluated at baseline, 1, and 7 months. Healthy controls were matched by age and sex.

resultsAt baseline, the combined PD group (n = 64) was significantly worse than healthy controls (n = 20) for SPL (P < 0.05) and CETI-M (P = 0.0001). At 1 and 7 months, SPL between-group comparisons showed greater improvements for LSVT LOUD (n = 22) than LSVT ARTIC (n = 20; P < 0.05) and UNTXPD (n = 22; P < 0.05). Sound pressure level differences between LSVT ARTIC and UNTXPD at 1 and 7 months were not significant (P > 0.05). For CETI-M, between-group comparisons showed greater improvements for LSVT LOUD and LSVT ARTIC than UNTXPD at 1 month (P = 0.02; P = 0.02). At 7 months, CETI-M between-group differences were not significant (P = 0.08). Within-group CETI-M improvements for LSVT LOUD were maintained through 7 months (P = 0.0011).

conclusionsLSVT LOUD showed greater improvements than both LSVT ARTIC and UNTXPD for SPL at 1 and 7 months. For CETI-M, both LSVT LOUD and LSVT ARTIC improved at 1 month relative to UNTXPD. Only LSVT LOUD maintained CETI-M improvements at 7 months. © 2018 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.

Indexed as

Treatment OutcomeAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedParkinson DiseaseSpeech DisordersSpeech TherapyarticulationParkinson's diseaseRCTspeech treatmentvoice

Identifiers

PMID30264896
PMCPMC6261685

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.