Evidence map›Paper›PMID 30264687›Full record

ArticleEpidemiology and infection2018

Child and adult spinal tuberculosis at tertiary hospitals in the Western Cape, South Africa: 4-year burden and trend.

T N Mann, H S Schaaf, R N Dunn, S Dix-Peek, K du Preez, R P Lamberts, J du Toit, J H Davis

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  6. Post-TB health and wellbeing.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
    Article
  7. Article
  8. Culture filtrate supplementation can be used to improveFrontiers in cellular and infection microbiology · 2022
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

T N MannDivision of Orthopaedic Surgery,Department of Surgical Sciences,Faculty of Medicine and Health Sciences,Stellenbosch University,Francie van Zijl Drive,Parow, 7505,Cape Town,South Africa.ORCID 0000-0002-9750-5106
H S SchaafDepartment of Paediatrics and Child Health,Faculty of Medicine and Health Sciences,Desmond Tutu TB Centre, Stellenbosch University,Francie van Zijl Drive, Parow,7505,Cape Town,South Africa.
R N DunnDivision of Orthopaedic Surgery, Department of Surgery,Faculty of Health Sciences,University of Cape Town,H49 Old Main Building, Groote Schuur Hospital,Observatory, 7925,Cape Town,South Africa.
S Dix-PeekDivision of Orthopaedic Surgery, Department of Surgery,Faculty of Health Sciences,University of Cape Town, Red Cross War Memorial Children's Hospital,Klipfontein Road,Rondebosch, 7700,Cape Town,South Africa.
K du PreezDepartment of Paediatrics and Child Health,Faculty of Medicine and Health Sciences,Desmond Tutu TB Centre, Stellenbosch University,Francie van Zijl Drive, Parow,7505,Cape Town,South Africa.
R P LambertsDivision of Orthopaedic Surgery,Department of Surgical Sciences,Faculty of Medicine and Health Sciences,Stellenbosch University,Francie van Zijl Drive,Parow, 7505,Cape Town,South Africa.
J du ToitDivision of Orthopaedic Surgery,Department of Surgical Sciences,Faculty of Medicine and Health Sciences,Stellenbosch University,Francie van Zijl Drive,Parow, 7505,Cape Town,South Africa.
J H DavisDivision of Orthopaedic Surgery,Department of Surgical Sciences,Faculty of Medicine and Health Sciences,Stellenbosch University,Francie van Zijl Drive,Parow, 7505,Cape Town,South Africa.
Stellenbosch University · ZADesmond Tutu HIV Foundation · ZAUniversity of Cape Town · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this retrospective review was to assess the overall burden and trend in spinal tuberculosis (TB) at tertiary hospitals in the Western Cape Province of South Africa. All spinal TB cases seen at the province's three tertiary hospitals between 2012 and 2015 were identified and clinical records of each case assessed. Cases were subsequently classified as bacteriologically confirmed or clinically diagnosed and reported with accompanying clinical and demographic information. Odds ratios (OR) for severe spinal disease and corrective surgery in child vs. adult cases were calculated. A total of 393 cases were identified (319 adults, 74 children), of which 283 (72%) were bacteriologically confirmed. Adult cases decreased year-on-year (P = 0.04), however there was no clear trend in child cases. Kyphosis was present in 60/74 (81%) children and 243/315 (77%) adults with available imaging. Corrective spinal surgery was performed in 35/74 (47%) children and 80/319 (25%) adults (OR 2.7, 95% confidence interval 1.6-4.5, P = 0.0003). These findings suggest that Western Cape tertiary hospitals have experienced a substantial burden of spinal TB cases in recent years with a high proportion of severe presentation, particularly among children. Spinal TB remains a public health concern with increased vigilance required for earlier diagnosis, especially of child cases.

Indexed as

Cost of IllnessAdolescentAdultChildChild, PreschoolFemaleHumansInfantKyphosisMaleMiddle AgedPrevalenceRetrospective StudiesSouth AfricaTertiary Care CentersTuberculosis, SpinalChildhood tuberculosisextra-pulmonary tuberculosisspinal tuberculosistuberculosis epidemiology

Identifiers

PMID30264687
PMCPMC6453008
OpenAlexW2893105340

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.