Evidence map›Paper›PMID 30264605›Full record

ArticleJournal of behavioral addictions2018

Gambling disorder and bilateral transcranial direct current stimulation: A case report.

Giovanni Martinotti, Eleonora Chillemi, Matteo Lupi, Luisa De Risio, Mauro Pettorruso, Massimo Di Giannantonio

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of behavioral addictions, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Giovanni Martinotti1 Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University , Chieti, Italy.
Eleonora Chillemi3 SRP "Villa Maria Pia" , Rome, Italy.
Matteo Lupi1 Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University , Chieti, Italy.
Luisa De Risio4 Institute of Psychiatry and Psychology, Fondazione Policlinico Universitario "A.Gemelli", Università Cattolica del Sacro Cuore , Rome, Italy.
Mauro Pettorruso1 Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University , Chieti, Italy.
Massimo Di Giannantonio1 Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University , Chieti, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGambling disorder (GD) is a major public health concern with currently no validated and efficacious treatments approved. In this single case study, we report the short- and long-term effect of bilateral transcranial direct current stimulation (tDCS) of dorsolateral prefrontal cortex (DLPFC) on craving and impulse control in a subject with GD.

methodsThe patient is a 26-year-old Caucasian male with an 8-year history of GD as well as alcohol and cocaine misuse. Treatment consisted of twice-a-day stimulation for 10 days. According to the literature, both the left (to control craving) and the right (to control emotional impulses) DLPFC were stimulated. Patients subsequently received tDCS once a week for 3 months and then once every 2 weeks for another 3 months.

resultsAfter 10 days of treatment, the subject reported improved psychiatric symptoms (depression, anxiety, and impulsivity), as well as reduced gambling craving symptom severity. After 3 and 6 months of treatment, the clinical picture further improved. DISCUSSION: This is the first report of tDCS effectiveness in a single case study of GD. Therapeutic effects, both on the addictive behavior and on psychiatric comorbid symptomatology, were lasting and continued over 6 months of tDCS maintenance treatment. Future case-control studies are required to test the efficacy of this tool in patients with GD.

Indexed as

Transcranial Direct Current StimulationAdultCravingGamblingHumansImpulsive BehaviorMalePrefrontal Cortexdorsolateral prefrontal cortexgambling disordertranscranical direct current stimulation

Identifiers

PMID30264605
PMCPMC6426396

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.