Evidence map›Paper›PMID 30264448›Full record

ArticleJournal of sleep research2019

PAP treatment in patients with OSA does not induce long-term nasal obstruction.

Maria Värendh, Morgan Andersson, Erla Björnsdóttir, Erna S Arnardóttir, Thorarinn Gislason, Allan I Pack, Harald Hrubos-Strøm, Arne Johannisson, Sigurdur Juliusson

Open access · hybridAbstract read
In one paragraph

Article in Journal of sleep research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023
    Review
  4. Article
  5. Nasal polyposis is a risk factor for nonadherence to CPAP treatment in sleep apnea: the population-based DISCOVERY study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Maria VärendhDepartment of Otorhinolaryngology, Head and Neck Surgery, Skåne University Hospital, Lund, Sweden.ORCID 0000-0001-8421-4804
Morgan AnderssonDepartment of Otorhinolaryngology, Head and Neck Surgery, Skåne University Hospital, Lund, Sweden.
Erla BjörnsdóttirSleep Department, Landspitali - The National University Hospital of Iceland, Reykjavík, Iceland.
Erna S ArnardóttirSleep Department, Landspitali - The National University Hospital of Iceland, Reykjavík, Iceland.
Thorarinn GislasonSleep Department, Landspitali - The National University Hospital of Iceland, Reykjavík, Iceland.
Allan I PackCenter for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Harald Hrubos-StrømDepartment of Otorhinolaryngology, Akershus University Hospital, Lørenskog, Norway.
Arne JohannissonDepartment of Health Sciences, Faculty of Medicine, Lund University, Lund, Sweden.
Sigurdur JuliussonDepartment of Otolaryngology, Head and Neck Surgery, Landspitali - The National University Hospital of Iceland, Reykjavík, Iceland.
Lund University · SEUniversity of Iceland · ISAkershus University Hospital · NOCircadian (United States) · USNational University Hospital of Iceland · IS

Funding

Family Linkage Study of Obstructive Sleep ApneaR01HL072067 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI PACK, ALLAN IAN · 2003 to 2007
$5.7M
NHLBI NIH HHS R01 HL072067NIH HHS R01HL072067
6 · The paper itself

Abstract

We hypothesized that positive airway pressure treatment would induce nasal obstruction and decrease nasal cavity due to mucosal swelling. We further hypothesized that subjective and objective nasal obstruction at baseline would negatively affect positive airway pressure adherence. A total of 728 patients with sleep apnea were investigated in the Icelandic Sleep Apnea Cohort at baseline and 2 years after starting positive airway pressure. Patients underwent home sleep apnea testing at baseline. Questionnaires were answered and acoustic rhinometry was completed at baseline and follow-up. The proportion of patients reporting subjective nocturnal nasal obstruction was reduced (baseline: 35% versus follow-up: 24%; p < 0.001). Small interior nasal dimensions increased (p < 0.001) independent of adherence to treatment. Small nasal volume at baseline was a determinant for becoming a non-user of positive airway pressure treatment (odds ratio 2.22, confidence interval 95% 1.35-3.67, p = 0.002). Subjective nasal obstruction decreased 2 years after initiating positive airway treatment in sleep apnea, and objectively small nasal dimensions increased. Small nasal volume at baseline was a negative predictor for positive airway pressure treatment adherence. Maybe most importantly, positive airway pressure treatment did not cause long-term objective or subjective nasal obstruction.

Indexed as

Cohort StudiesContinuous Positive Airway PressureFemaleHumansMaleMiddle AgedNasal ObstructionProspective StudiesRhinometry, AcousticSleep Apnea, ObstructiveSurveys and Questionnairesacoustic measurementsadherenceapneabreathingnasal anatomynosesurvey

Identifiers

PMID30264448
PMCPMC7379236
OpenAlexW2893058455

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.