Evidence map›Paper›PMID 30264380›Full record

ReviewIntensive care medicine2018

Conflicts of interest disclosure forms and management in critical care clinical practice guidelines.

Waleed Alhazzani, Kimberley Lewis, Roman Jaeschke, Bram Rochwerg, Morten Hylander Møller, Laura Evans, Kevin C Wilson, Sheena Patel, Craig M Coopersmith, Maurizio Cecconi and 2 more

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Intensive care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07563842 (Expert Consensus On Definitions And Management Of Intra-Abdominal Hypertension And Abdominal Compartment Syndrome), which is not on this map. Cited by 21 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07563842 enrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Expert Consensus On Definitions And Management Of Intra-Abdominal Hypertension And Abdominal Compartment Syndrome

Typeobservational_patient_registrySponsorMedical University of LublinRan2025 to 2026Enrolled60ConditionsAbdominal Hypertension, Abdominal Compartment SyndromeArmsDelphi study
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Guideline
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  6. Pooled it
  7. Pooled it
  8. Guideline
  9. Guideline
  10. Article
  11. Review
  12. ENGINE-An EHS Project for Future Guidelines.Journal of abdominal wall surgery : JAWS · 2024
    Article
  13. Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Waleed AlhazzaniDepartment of Medicine, Division of Critical Care, St Joseph's Healthcare Hamilton, McMaster University, 50 Charlton Avenue, Hamilton, ON, L8N 4A6, Canada. alhazzaw@mcmaster.ca.
Kimberley LewisDepartment of Medicine, Division of Critical Care, St Joseph's Healthcare Hamilton, McMaster University, 50 Charlton Avenue, Hamilton, ON, L8N 4A6, Canada.
Roman JaeschkeDepartment of Medicine, Division of Critical Care, St Joseph's Healthcare Hamilton, McMaster University, 50 Charlton Avenue, Hamilton, ON, L8N 4A6, Canada.
Bram RochwergDepartment of Medicine, Division of Critical Care, St Joseph's Healthcare Hamilton, McMaster University, 50 Charlton Avenue, Hamilton, ON, L8N 4A6, Canada.
Morten Hylander MøllerDepartment of Intensive Care 4131, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Laura EvansDivision of Pulmonary, Critical Care and Sleep Medicine, New York University School of Medicine, New York, USA.
Kevin C WilsonDepartment of Medicine, Boston University School of Medicine, Boston, MA, USA.
Sheena PatelAmerican College of Chest Physicians (CHEST), Glenview, IL, USA.
Craig M CoopersmithDepartment of Surgery and Emory Critical Care Center, Emory University, Atlanta, USA.
Maurizio CecconiHumanitas Clinical and Research Center, Milan, Italy.
Gordon GuyattDepartment of Medicine, Division of Critical Care, St Joseph's Healthcare Hamilton, McMaster University, 50 Charlton Avenue, Hamilton, ON, L8N 4A6, Canada.
Elie A AklDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTrustworthy clinical practice guidelines (CPGs) require identification and careful management of conflicts of interest (COIs) among all participants in the guideline development. Furthermore, COIs are more common than anticipated. However, there are no universally accepted methods to identify and manage COIs.

objectiveTo describe and summarize the current COI disclosure forms and management policies in selected critical care professional societies that develop high-impact CPGs. In addition, we aim to provide suggestions to guideline developers on how to identify and manage different types of COIs.

methodsWe searched PubMed and MEDLINE for CPGs published between 2013 and 2018 in English language and addressed general critical care topics. We then ranked the CPGs according to the numbers of citations and selected the first five critical care professional societies that sponsored the guidelines. We obtained the most recent COI declaration forms and management policies. Two reviewers abstracted data on different types of COI in each of the disclosure forms and management policies.

resultsAll selected professional critical care societies require that members declare direct financial COIs; four societies inquire specifically about intellectual COIs (involvement in primary research). Three out of five societies require members to disclose indirect institutional financial COIs; however, none inquire about other forms of institutional COI. We developed, by consensus, a streamlined framework to classify and manage different types of COIs.

conclusionThe current COI disclosure forms of selected professional societies provide more attention to financial disclosures and COIs and less attention to detecting and managing intellectual COIs, while rarely addressing institutional COIs. We provide some suggestions for guideline developers on the classification and management of different COIs in the context of CPGs.

Indexed as

Biomedical ResearchConflict of InterestCritical CareDisclosureHumansPractice Guidelines as TopicClinical practice guidelinesConflict of interestCritical care

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.