Evidence map›Paper›PMID 30264215›Full record

Observational studyPediatric nephrology (Berlin, Germany)2019

Predictors of patency for arteriovenous fistulae and grafts in pediatric hemodialysis patients.

Ali Mirza Onder, Joseph T Flynn, Anthony A Billings, Fang Deng, Marissa DeFreitas, Chryso Katsoufis, Matthew M Grinsell, Larry T Patterson, Jennifer Jetton, Sahar Fathallah-Shaykh and 20 more

Erratum issuedAbstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Pediatric nephrology (Berlin, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

30 authors at 20 institutions in 1 country.

Ali Mirza OnderDivision of Pediatric Nephrology, Le Bonheur Children's Hospital, University of Tennessee, School of Medicine, 49 N Dunlop Street, Faculty Office Building, Room 322, Memphis, TN, 38105, USA. aonder@uthsc.edu.ORCID 0000-0002-5225-0525
Joseph T FlynnDivision of Nephrology, Seattle Children's Hospital, Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA.
Anthony A BillingsDepartment of Statistics, West Virginia University, Morgantown, WV, USA.
Fang DengKidney Diseases Division, Feinberg School of Medicine, Northwestern University and the Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL, USA.
Marissa DeFreitasDepartment of Pediatrics, Division of Pediatric Nephrology, Holtz Children's Hospital, University of Miami Leonard M Miller School of Medicine, Miami, FL, USA.
Chryso KatsoufisDepartment of Pediatrics, Division of Pediatric Nephrology, Holtz Children's Hospital, University of Miami Leonard M Miller School of Medicine, Miami, FL, USA.
Matthew M GrinsellDivision of Pediatric Nephrology, Primary Children's Hospital, University of Utah, Salt Lake City, UT, USA.
Larry T PattersonDivision of Pediatric Nephrology, Children's National Health System, Washington, DC, USA.
Jennifer JettonDivision of Nephrology, Dialysis and Transplantation, University of Iowa Stead Family Children's Hospital, Iowa City, IA, USA.
Sahar Fathallah-ShaykhDivision of Pediatric Nephrology, Children's of Alabama, University of Alabama, Birmingham, AL, USA.
Daniel RanchDivision of Pediatric Nephrology, University of Texas Health Science Center, San Antonio, TX, USA.
Diego AvilesDivision of Pediatric Nephrology, Children's Hospital New Orleans, LSU Heath School of Medicine, New Orleans, LA, USA.
Lawrence CopelovitchDivision of Nephrology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Eileen EllisDivision of Pediatric Nephrology, Arkansas Children's Hospital, Little Rock, AR, 72202, USA.
Vimal ChandaDivision of Pediatric Nephrology, Children's Mercy Hospital, Kansas City, MO, USA.
Ayah ElmaghrabiDivision of Pediatric Nephrology, Children's Medical Center Dallas, UT Southwestern, Dallas, TX, USA.
Jen-Jar LinDivision of Pediatric Nephrology, Brenner Children's Hospital, Wake Forest University, Winston Salem, NC, USA.
Lavjay ButaniDivision of Pediatric Nephrology, UC Davis Children's Hospital, Sacramento, CA, USA.
Maha HaddadDivision of Pediatric Nephrology, UC Davis Children's Hospital, Sacramento, CA, USA.
Olivera Marsenic CoulouresDivision of Pediatric Nephrology, Yale New Haven Children's Hospital, Yale University School of Medicine, New Haven, CT, 06504, USA.
Paul BrakemanDivision of Pediatric Nephrology, UCSF Benioff Children's Hospital, San Francisco, CA, USA.
Raymond QuigleyDivision of Pediatric Nephrology, Children's Medical Center Dallas, UT Southwestern, Dallas, TX, USA.
H Stella ShinDivision of Pediatric Nephrology, Children's Healthcare of Atlanta, Atlanta, GA, USA.
Rouba GarroDivision of Pediatric Nephrology, Children's Healthcare of Atlanta, Atlanta, GA, USA.
Hui LiuDepartment of Urology, UCLA School of Medicine, Los Angeles, CA, USA.
Javad RahimikolluDepartment of Statistics, West Virginia University, Morgantown, WV, USA.
Rupesh RainaDivision of Pediatric Nephrology, Akron Children's Hospital, Akron, OH, USA.
Craig B LangmanKidney Diseases Division, Feinberg School of Medicine, Northwestern University and the Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL, USA.
Ellen G WoodDepartment of Pediatrics, Division of Pediatric Nephrology, SSM Cardinal Glennon Children's Hospital, Saint Louis University, St. Louis, MO, USA.
Midwest Pediatric Nephrology Consortium
Children's Healthcare of Atlanta · USChildren's Medical Center · USNorthwestern University · USUC Davis Children's Hospital · USUniversity of Miami Hospital · USWest Virginia University · USAkron Children's Hospital · USArkansas Children's Hospital · USBrenner Children's Hospital · USCardinal Glennon Children’s Medical Center · USChildren's Hospital of New Orleans · USChildren's Hospital of Philadelphia · USChildren's Mercy Hospital · USChildren's National · USLe Bonheur Children's Hospital · USPrimary Children's Hospital · USSeattle Children's Hospital · USThe University of Texas Health Science Center at San Antonio · USUCSF Benioff Children's Hospital · USUniversity of Alabama · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHemodialysis (HD) guidelines recommend permanent vascular access (PVA) in children unlikely to receive kidney transplant within 1 year of starting HD. We aimed to determine predictors of primary and secondary patency of PVA in pediatric HD patients.

methodsRetrospective chart reviews were performed for first PVAs in 20 participating centers. Variables collected included patient demographics, complications, interventions, and final outcome.

resultsThere were 103 arterio-venous fistulae (AVF) and 14 AV grafts (AVG). AVF demonstrated superior primary (p = 0.0391) and secondary patency (p = 0.0227) compared to AVG. Primary failure occurred in 16 PVA (13.6%) and secondary failure in 14 PVA (12.2%). AVF were more likely to have primary failure (odds ratio (OR) = 2.10) and AVG had more secondary failure (OR = 3.33). No demographic, clinical, or laboratory variable predicted primary failure of PVA. Anatomical location of PVA was predictive of secondary failure, with radial having the lowest risk compared to brachial (OR = 12.425) or femoral PVA (OR = 118.618). Intervention-free survival was predictive of secondary patency for all PVA (p = 0.0252) and directly correlated with overall survival of AVF (p = 0.0197) but not AVG. Study center demonstrated statistically significant effect only on intervention-free AVF survival (p = 0.0082), but not number of complications or interventions, or outcomes.

conclusionsIn this multi-center pediatric HD cohort, AVF demonstrated primary and secondary patency advantages over AVG. Radial PVA was least likely to develop secondary failure. Intervention-free survival was the only predictor of secondary patency for AVF and directly correlated with overall access survival. The study center effect on intervention-free survival of AVF deserves further investigation.

Indexed as

Vascular PatencyAdolescentArteriovenous Shunt, SurgicalCanadaChildFemaleHumansKidney Failure, ChronicMaleRenal DialysisRetrospective StudiesRisk FactorsTime FactorsTreatment FailureUnited StatesVascular GraftingArteriovenous fistulaArteriovenous graftPediatric hemodialysisPrimary patencySecondary patency

Identifiers

PMID30264215
OpenAlexW2893873479

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.